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Papers Written by TUS Faculty Members Introduced in "Medicine Innovates"

Japanese

Papers written by Professor Shin Aoki, et al., of the Department of Medicinal and Life Sciences, Faculty of Pharmaceutical Sciences were introduced in "Medicine Innovates."

[Featured Papers]

  1. 1. Cancer cells were detected by combining death receptors expressed on cell membranes of cancer cells and the design and synthesis of an artificial death ligand (light-emitting iridium (III) complex--peptide hybrid) that induces apoptosis, which is a type of programmed cell death.
    Abdullah-Al Masum, Kenta Yokoi, Yosuke Hisamatsu, Kana Naito, Babita Shashni, and Shin Aoki, "Design and Synthesis of a Luminescent Iridium Complex-Peptide (IPH) that Detects Cancer Cells and Induces Their Apoptosis"
    Bioorganic & Medicinal Chemistry, 2018, 26 (17), 4804-4816

  2. 2. A glass-bead filter (GBF) for easily isolating, cultivating and re-collecting circulating tumor cells (CTCs), which are considered as being related to the metastasis and recurrence of cancer, and PC software for CTC detection were developed.
    Babita Shashni, Hidehiko Matsuura, Riku Saito, Takuma Hirata, Shinya Ariyasu, Kenta Nomura, Hiroshi Takemura, Kazunori Akimoto, Naoyuki Aikawa, Atsuo Yasumori and Shin Aoki, "Simple and Convenient Method for the Isolation, Culture, and Re-collection of Cancer Cells from Blood by Using Glass-Bead Filters"
    ACS Biomaterials Science & Engineering, 2019, 5 (2), 438-452 (DOI: 10.1021/acsbiomaterials.8b01335)

Please see the following websites to see the featured papers.

1. Artificial Death Ligands (Luminescent Detectors and Killers of Cancer Cells)
https://medicineinnovates.com/luminescent-detectors-killers-cancer-cells/

2. GBF to isolate, cultivate, and re-collect CTCs (Let's Trap Cancer Cells from Blood, Grow, Re-collect, and Analyze Them)
https://medicineinnovates.com/trap-cancer-cells-blood-grow-re-collect-analyze/

Aoki Laboratory
Official University page : https://www.tus.ac.jp/en/fac/p/index.php?3f7d
Laboratory homepage: https://www.rs.noda.tus.ac.jp/~aokilab/

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