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Improvement of the solubility and intestinal absorption of curcumin by N-acyl taurates and elucidation of the absorption-enhancing mechanisms.
[ 全著者名 ] Xinpeng Li, Ami Kawamura, Yusuke Sato, Masaki Morishita, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto.
[ 掲載誌名 ] Biological and Pharmaceutical Bulletin
[ 掲載年月 ] 2017年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Development of PEGylated carboxylic acid-modified polyamidoamine dendrimers as bone-targeting carriers for the treatment of bone diseases.
[ 全著者名 ] Shugo Yamashita Hidemasa Katsumi Nozomi Hibino Yugo Isobe Yumiko Yagi Kosuke Kusamori Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Journal of Controlled Release
[ 掲載年月 ] 2017年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Using size-controlled multicellular spheroids of murine adenocarcinoma cells to efficiently establish pulmonary tumors in mice.
[ 全著者名 ] Tomoko Nishikawa Yutaro Tanaka Makiya Nishikawa Kosuke Kusamori Narumi Mizuno Yuya Mizukami Yuka Ogino Kazunori Shimizu Satoshi Konishi Yuki Takahashi Yoshinobu Takakura.
[ 掲載誌名 ] Biotechnology Journal
[ 掲載年月 ] 2017年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Effects of manufacturing methods on dissolution and absorption of ketoconazole in the presence of organic acid as a pH modifier.
[ 全著者名 ] Masashi Adachi Yuta Hinatsu Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Manabu Nakatani Koichi Wada Akira Yamamoto
[ 掲載誌名 ] AAPS PharmSciTech
[ 掲載年月 ] 2017年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Optimization of albumin secretion and metabolic activity of cytochrome P450 1A1 of human hepatoblastoma HepG2 cells in multicellular spheroids by controlling spheroid size.
[ 全著者名 ] Tomoko Nishikawa Yutaro Tanaka Makiya Nishikawa Yuka Ogino Kosuke Kusamori Narumi Mizuno Yuya Mizukami Kazunori Shimizu Satoshi Konishi Yuki Takahashi Yoshinobu Takakura
[ 掲載誌名 ] Biological and Pharmaceutical Bulletin
[ 掲載年月 ] 2017年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Nasal Drug Absorption from Powder Formulations: Effect of Fluid Volume Changes on the Mucosal Surface.
[ 全著者名 ] Akiko Tanaka, Tomoyuki Furubayashi, Enomura Yuki, Hori Tomoki, Shimomura Rina, Maeda Chiaki, Shunsuke Kimura, Daisuke Inoue, Kosuke Kusamori, Hidemasa, Katsumi, Toshiyasu Sakane, Akira Yamamoto.
[ 掲載誌名 ] Biological and Pharmaceutical Bulletin
[ 掲載年月 ] 2017年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Nasal drug absorption from powder formulations: The effect of three types of hydroxypropyl cellulose (HPC).
[ 全著者名 ] Akiko Tanaka Tomoyuki Furubayashi Manami Tomisaki Mayuko Kawakami Shunsuke Kimura Daisuke Inoue Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] European Journal of Pharmaceutical Sciences
[ 掲載年月 ] 2017年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
ヒアルロン酸を素材とする溶解型マイクロニードルを利用した糖尿病治療薬の経皮吸収性の改善
[ 全著者名 ] 山本 昌、勝見英正、草森浩輔、坂根稔康
[ 掲載誌名 ] Japanese Journal of Pharmaceutical and Diabetes
[ 掲載年月 ] 2017年
[ 著作区分 ] レフェリー付学術論文(日本語)
Enhanced oral delivery of alendronate by sucrose fatty acids esters in rats and their absorption-enhancing mechanisms.
[ 全著者名 ] Tammam Alama Hiroko Katayama Sachiko Hirai Shizuka Ono Ayumi Kajiyama Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] International Journal of Pharmaceutics
[ 掲載年月 ] 2016年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Enhanced oral delivery of bisphosphonate by novel absorption enhancers: improvement of intestinal absorption of alendronate by N-acyl amino acids and N-acyl taurates and their absorption-enhancing mechanisms.
[ 全著者名 ] Yuka Nakaya Mayu Takaya Yuta Hinatsu Tammam Alama Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Journal of Pharmaceutical Sciences
[ 掲載年月 ] 2016年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Effects of 2 polyoxyethylene alkyl ethers on the function of intestinal P-glycoprotein and their inhibitory mechanisms.
[ 全著者名 ] Wanting Zhao Tammam Alama Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Journal of Pharmaceutical Sciences
[ 掲載年月 ] 2016年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Permeation of sumatriptan succinate across human skin using multiple types of self-dissolving microneedle arrays fabricated from sodium hyaluronate.
[ 全著者名 ] Dan Wu Hidemasa Katsumi Ying-shu Quan Fumio Kamiyama Kosuke Kusamori Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Journal of Drug Targeting
[ 掲載年月 ] 2016年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Effects of polyoxyethylene alkyl ethers on the intestinal transport and absorption of rhodamine 123: a P-glycoprotein substrate by in vitro and in vivo studies.
[ 全著者名 ] Wanting Zhao Sachiyo Uehera Keiichiro Tanaka Shuhei Tadokoro Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Journal of Pharmaceutical Sciences
[ 掲載年月 ] 2016年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Absorption-enhancing effects of gemini surfactant on the intestinal absorption of poorly absorbed hydrophilic drugs including peptide and protein drugs in rats.
[ 全著者名 ] Tammam Alama Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] International Journal of Pharmaceutics
[ 掲載年月 ] 2016年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Importance of the direct contact of amorphous solid particles with the surface of monolayers for the transepithelial permeation of curcumin.
[ 全著者名 ] Shunsuke Kimura Sachiha Kasatani Megumi Tanaka Kaeko Araki Masakazu Enomura Kei Moriyama Daisuke Inoue Tomoyuki Furubayashi Akiko Tanaka Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Molecular Pharmaceutics
[ 掲載年月 ] 2016年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Improvement of transdermal delivery of exendin-4 using novel tip-loaded microneedle arrays fabricated from hyaluronic acid.
[ 全著者名 ] Shu Liu Dan Wu Ying-shu Quan Fumio Kamiyama Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Molecular Pharmaceutics
[ 掲載年月 ] 2016年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Increased insulin secretion from insulin-secreting cells by construction of mixed multicellular spheroids.
[ 全著者名 ] Kosuke Kusamori Makiya Nishikawa Narumi Mizuno Tomoko Nishikawa Akira Masuzawa Yutaro Tanaka Yuya Mizukami Kazunori Shimizu Satoshi Konishi Yuki Takahashi Yoshinobu Takakura
[ 掲載誌名 ] Pharmaceutical Research
[ 掲載年月 ] 2016年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Development of a drug-coated microneedle array and its application for transdermal delivery of interferon alpha.
[ 全著者名 ] Kosuke Kusamori Hidemasa Katsumi Ryota Sakai Rie Hayashi Yuka Hirai Yutaro Tanaka Kaori Hitomi Ying-shu Quan Fumio Kamiyama Keigo Yamada Shun-ichiro Sumida Kazumasa Kishi Katsuhiko Hashiba Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Biofabrication
[ 掲載年月 ] 2016年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Improved dissolution and absorption of ketoconazole in the presence of organic acids as pH-modifiers.
[ 全著者名 ] Masashi Adachi Yuta Hinatsu Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Manabu Nakatani Koichi Wada Akira Yamamoto
[ 掲載誌名 ] European Journal of Pharmaceutical Sciences
[ 掲載年月 ] 2015年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Improvement of transdermal delivery of sumatriptan succinate using a novel self-dissolving microneedle array fabricated from sodium hyaluronate in rats.
[ 全著者名 ] Dan Wu Ying-shu Quan Fumio Kamiyama Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Biological and Pharmaceutical Bulletin
[ 掲載年月 ] 2015年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Synthetic molecules that protect cells from anoikis and their use in cell transplantation.
[ 全著者名 ] Heidie L. Frisco-Cabanos Mizuki Watanabe Naoki Okumura Kosuke Kusamori Naohiro Takemoto Junichiro Takaya Shin-ichi Sato Sayumi Yamazoe Yoshinobu Takakura Shigeru Kinoshita Makiya Nishikawa Noriko Koizumi Motonari Uesugi
[ 掲載誌名 ] Angewandte Chemie International Edition
[ 掲載年月 ] 2014年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Pharmacokinetics and preventive effects of platinum nanoparticles as reactive oxygen species scavengers on hepatic ischemia/reperfusion injury in mice.
[ 全著者名 ] Hidemasa Katsumi Kentaro Fukui Kanako Sato Shoko Maruyama Shugo Yamashita Erika Mizumoto Kosuke Kusamori Munetaka Oyama Masataka Sano Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Metallomics
[ 掲載年月 ] 2014年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice.
[ 全著者名 ] Hidemasa Katsumi Makiya Nishikawa Kazushi Nishiyama Rikiya Hirosaki Narumi Nagamine Haruka Okamoto Hironori Mizuguchi Kosuke Kusamori Hiroyuki Yasui Fumiyoshi Yamashita Mitsuru Hashida Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] Free Radical Biology and Medicine
[ 掲載年月 ] 2014年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Transdermal delivery of relatively high molecular weight drugs using novel self-dissolving microneedle arrays fabricated from hyaluronic acid and their characteristics and safety after application to the skin.
[ 全著者名 ] Shu Liu Mei-na Jin Ying-shu Quan Fumio Kamiyama Kosuke Kusamori Hidemasa Katsumi Toshiyasu Sakane Akira Yamamoto
[ 掲載誌名 ] European Journal of Pharmaceutics and Biopharmaceutics
[ 掲載年月 ] 2014年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
マイクロニードルを用いたペプチド・タンパク性医薬品の次世代型経皮吸収製剤の開発
[ 全著者名 ] 勝見英正 権 英淑 神山文男 草森浩輔 坂根稔康 山本 昌
[ 掲載誌名 ] YAKUGAKU ZASSHI
[ 掲載年月 ] 2014年 1月
[ 著作区分 ] レフェリー付学術論文(日本語)
Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice.
[ 全著者名 ] Kosuke Kusamori Makiya Nishikawa Narumi Mizuno Tomoko Nishikawa Akira Masuzawa Kazunori Shimizu Satoshi Konishi Yuki Takahashi Yoshinobu Takakura
[ 掲載誌名 ] Journal of Controlled Release
[ 掲載年月 ] 2014年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
難吸収性薬物の消化管吸収性に及ぼす各種ショ糖脂肪酸エステルの影響
[ 全著者名 ] 山本 昌 勝見英正 草森浩輔 坂根稔康
[ 掲載誌名 ] YAKUGAKU ZASSHI
[ 掲載年月 ] 2014年 1月
[ 著作区分 ] レフェリー付学術論文(日本語)
Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice.
[ 全著者名 ] Mai Ikemura Makiya Nishikawa Kosuke Kusamori Miho Fukuoka Fumiyoshi Yamashita Mitsuru Hashida
[ 掲載誌名 ] Journal of Controlled Release
[ 掲載年月 ] 2013年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Small molecule-induced clustering of heparan sulfate promotes cell adhesion.
[ 全著者名 ] Naohiro Takemoto Tetsuya Suehara Heidie L. Frisco Shin-ichi Sato Takuhito Sezaki Kosuke Kusamori Yoshinori Kawazoe Sun Min Park Sayumi Yamazoe Yoshiyuki Mizuhata Rintaro Inoue Gavin J. Miller Steen U. Hansen Gordon C. Jayson John M. Gardiner Toshiji Kanaya Norihiro Tokitoh Kazumitsu Ueda Yoshinobu Takakura Noriyuki Kioka Makiya Nishikawa Motonari Uesugi
[ 掲載誌名 ] Journal of the American Chemical Society
[ 掲載年月 ] 2013年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Poly (N-isopropylacrylamide) coated microwell arrays for construction and recovery of multicellular spheroids.
[ 全著者名 ] Kazunori Shimizu Kosuke Kusamori Makiya Nishikawa Narumi Mizuno Tomoko Nishikawa Akira Masuzawa Shingo Katano Yuki Takahashi Yoshinobu Takakura Satoshi Konishi
[ 掲載誌名 ] Journal of Biosciences and Bioengineering
[ 掲載年月 ] 2013年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
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