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Design, Synthesis, and Biological Evaluation of Optically Active Cyclometalated Iridium(III) Complex-Peptide Hybrids Obtained by Optical Resolution via Diastereomeric Stereoisomers
[ 共同発表者名 ] Shin Aoki
[ 学会・会議名 ] The 19th Annual Congress of International Drug Discovery Science and Technology 2023 (IDDST-2023)
[ 発表日付 ] 2023年5月8日 ~ 5月10日
Induction of Paraptosis, a Class of Programmed Cell Death, in Cancer Cells by the Hybrid Compounds of Cyclometalated Iridium(III) Complexes and Triptycenes with Peptides
[ 共同発表者名 ] Shin Aoki
[ 学会・会議名 ] The 5th International Conference on Pharma Research and Development (Pharma R & D 2023)
[ 発表日付 ] 2023年2月20日 ~ 2月22日
Development of Cyclometalated Iridium(III) Complex-Peptide Hybrids that Induce Cell Death in Cancer Cells and Detect Dead Cells
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Azusa Kanbe, Nozomi Narushima, Chandrasekar Balachandran, Masaki Kakihana
[ 学会・会議名 ] 27th International SPACC Symposium
[ 発表日付 ] 2022年12月10日 ~ 12月11日
Design and Synthesis of Metal Complex-Peptide Hybirds that Possess Dual Functions as Paraptosis Inducers in Cancer Cells and Detectors of Dead Cells
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Chandrasekar Balachandran, Azusa Kanbe
[ 学会・会議名 ] The 10th Asian Symposium on Bioinorganic Chemistry (AsBIC10)
[ 発表日付 ] 2022年11月28日 ~ 12月3日
シクロメタレート型イリジウム錯体とトリプチセンのペプチドハイブリッド化合物によるがん細胞のプログラム細胞死誘導とメカニズム解析
[ 共同発表者名 ] 青木伸、横井健汰、山口晃平、新居真由香、Chandrasekar Balachandran
[ 学会・会議名 ] 第16回バイオ関連化学シンポジウム
[ 発表日付 ] 2022年9月10日 ~ 9月12日
Design and Synthesis of Hybrid Compounds of Cyclometalated Iridium(III) Complexes and Triptycenes with Basic Peptides that Induce Paraptosis in Cancer Cells
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Kohei Yamaguchi, Azusa Kanbe, Mayuka Nii, Chandrasekar Balachandran, Masaki Kakihana
[ 学会・会議名 ] The 3rd International Conference on Pharmacology and Toxicology
[ 発表日付 ] 2022年8月29日 ~ 8月30日
Development of New Cyclometalated Iridium(III) Complexes for Induction of Programmed Cell Death, Detection of Dead Cells, and Mechanistic Study
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Chandrasekar Balachandran, and Kohei Yamaguchi
[ 学会・会議名 ] Baltic Conference and Fellow Summit, IAAM (International Association of Advanced Materials)
[ 発表日付 ] 2022年8月28日 ~ 8月31日
Induction of Paraptotic Cell Death in Cancer Cells Induced by the Hybrid Compounds of Cyclometalated Iridium(III) Complexes and Triptylenes with Amphiphilic Peptides
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Chandrasekar Balachandran
[ 学会・会議名 ] The 8th Asian Congress on Coordination Chemistry (ACCC8)
[ 発表日付 ] 2022年8月7日 ~ 8月11日
Development of New Cyclometalated Iridium(III) Complexes for Induction of Programmed Cell Death, Detection of Dead Cells, and Mechanistic Study
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Chandrasekar Balachandran
[ 学会・会議名 ] The 8th Asian Congress on Coordination Chemistry (ACCC8)
[ 発表日付 ] 2022年8月7日 ~ 8月11日
Induction of Paraptosis in Cancer Cells by Cyclometalated Iridium(III) Complex-Peptide Hybrids via Intracellular Ca2+-Dependent Pathway
[ 共同発表者名 ] Kenta Yokoi, Chandrasekar, Balachandran, Jebiti Haribabu, Masakazu Umezawa, Koji Tsuchiya, Shin Aoki
[ 学会・会議名 ] The 4th International Webinar on Chemistry and Pharmaceutical Chemistry
[ 発表日付 ] 2022年3月11日 ~ 3月12日
Induction of Paraptosis in Cancer Cells by Cyclometalated Iridium (III) Complex-Peptide Hybrids via Intracellular Ca2 +-Dependent Pathway.
[ 共同発表者名 ] Kenta Yokoi, Chandrasekar, Balachandran, Jebiti Haribabu, Masakazu Umezawa, Koji Tsuchiya, Shin Aoki.
[ 学会・会議名 ] The 4th International Webinar on Chemistry and Pharmaceutical Chemistry.
[ 発表日付 ] 2022年3月11日 ~ 3月12日
Design, Synthesis and Anticancer Activity of Cyclometalated Iridium (III) Complex-Peptide Hybrid that Have a Cationic Cyclic Peptide.
[ 共同発表者名 ] Arisa Koyamada, Kenta Yokoi, Chandrasekar Balachandran, Masakazu Umezawa, Koji Tsuchiya, and Shin Aoki.
[ 学会・会議名 ] International Chemical Congress of Pacific Basin Societies (PACICHEM2020 / 2021)
[ 発表日付 ] 2021年12月16日 ~ 12月21日
Induction of Paraptosis in Cancer Cells by Cyclometalated Iridium (III) Complex-Peptide Hybrids and Its Mechanistic Study.
[ 共同発表者名 ] Kenta Yokoi, Jebiti Haribabu, Chandrasekar Balachandran, Masakazu Umezawa, Koji Tsuchiya, Shin Aoki.
[ 学会・会議名 ] 13th AFMC International Medicinal Chemistry Symposium (AIMECS 2021)
[ 発表日付 ] 2021年11月29日 ~ 12月2日
Design and Synthesis of Poly (2,2'-bipyridyl) Ligands Directed toward Chelation Therapy of Cancer.
[ 共同発表者名 ] Masumi Hirose, Zhu Jun Jie, Chandrasekar Balacahndran, Tomohiro Tanaka, Yosuke Hisamatsu, Yasuyuki Yamada, Shin Aoki.
[ 学会・会議名 ] International Research Network Initiative (IRNI) and 8th International Postgraduate Conference on Pharmaceutical Sciences 2021 (iPoPS2021)
[ 発表日付 ] 2021年9月28日 ~ 9月29日
Evaluation of cancer cell death-inducing activity of cyclometallate-type iridium complex-peptide hybrid and analysis of calcium-dependent induction mechanism
[ 共同発表者名 ] Kenta Yokoi, C. Balachandran, Shin Aoki
[ 学会・会議名 ] The 141st Annual Meeting of the Pharmaceutical Society of Japan
[ 発表日付 ] 2021年3月26日 ~ 3月28日
Design, Synthesis and Anticancer Activity of Bis-, and Mono(Cationic Peptide) Hybrids of Cyclometalated Iridium(III) Complexes: Effect of the Number of Peptide Units on Anticancer Property
[ 共同発表者名 ] Haribabu Jebiti, Kenta Yokoi, Yuichi Tamura, C. Balachandran, and Shin Aoki
[ 学会・会議名 ] 70th Conference of the Society of Complex Chemists (Online)
[ 発表日付 ] 2020年9月28日 ~ 9月30日
Design, synthesis and biological evaluation of cyclometallate-type iridium complex-peptide hybrids that induce calcium-dependent cancer cell death.
[ 共同発表者名 ] Kenta Yokoi, C. Balachandran, Shin Aoki
[ 学会・会議名 ] The 64th Annual Meeting of the Pharmaceutical Society of Japan
[ 発表日付 ] 2020年9月20日
Design, Synthesis and Anticancer Properties of Bis-, and Mono (Cationic Peptide) Hybrids of Ir (III) Complexes: Effect of the Number of Peptide Units on Anticancer Activity
[ 共同発表者名 ] Haribabu Jebiti, Yuichi Tamura, Kenta Yokoi, C. Balachandran, and Shin Aoki
[ 学会・会議名 ] 64th Annual Meeting of the Pharmaceutical Society of Japan
[ 発表日付 ] 2020年9月19日
Amphiphilic Cationic Triscyclometalated Iridium(III) Complex-Peptide Hybrids Induce Paraptosis-like Cell Death of Cancer Cells via Intracellular Ca2+-Dependent Pathways.
[ 共同発表者名 ] Kenta Yokoi, C. Balachandran, Aleksandra Mitrić, Shin Aoki
[ 学会・会議名 ] The 100th Annual Meeting of the Chemical Society of Japan
[ 発表日付 ] 2020年3月22日 ~ 3月25日
Cyclometalated Iridium(III)-Peptide Hybrids (IPHs) Increase a Cytosolic Ca2+ Overload from Endoplasmic Reticulum (ER) and its Subsequent Influx into Mitochondria that Trigger a Paraptosis Cell Death in Cancer Cells.
[ 共同発表者名 ] C. Balachandran, Kenta Yokoi, Kana Naito, Shin Aoki
[ 学会・会議名 ] 7th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2020)
[ 発表日付 ] 2020年2月28日 ~ 2月29日
Design and Synthesis of Poly(2,2’-bipyridyl) Ligands and Controlled of Cytotoxicity by Metal Complexation.
[ 共同発表者名 ] Masumi Hirose, C. Balachandran, Zhu Jun Jie, and Shin Aoki
[ 学会・会議名 ] 7th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2020)
[ 発表日付 ] 2020年2月28日 ~ 2月29日
Design, Synthesis, Bioimaging and Anticancer Properties of Mono-, and Disubsituted Cyclometalated Ir(III) Complex-Peptide Hybrids.
[ 共同発表者名 ] Jebiti Haribabu, Yuichi Tamura, C. Balachandran, Kenta Yokoi, and Shin Aoki
[ 学会・会議名 ] 7th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2020)
[ 発表日付 ] 2020年2月28日 ~ 2月29日
Cyclometalated Iridium(III)-Peptide Hybrids (IPHs) Induce a Paraptosis Mediated Cell Death in Cancer Cells
[ 共同発表者名 ] C. Balachandran, Kenta Yokoi, Kana Naito, Shin Aoki
[ 学会・会議名 ] Joined 6th symposium of Tokyo University of Science and Nippon Medical University
[ 発表日付 ] 2019年12月14日
Induction and mechanism analysis of programmed cell death of cancer cells using the luminescence function of iridium complex-peptide hybrid
[ 共同発表者名 ] 20. Kenta Yokoi, C. Balachandran, Aleksandra Mitrić, Shin Aoki
[ 学会・会議名 ] Symposium of Imaging Frontier Center, Tokyo University of Science
[ 発表日付 ] 2019年12月14日
Post-Complexation Functionalization of Cyclometalated Iridium Complexes and Its Applications to Biomedical and Material Sciences
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Ayami Kazama, C. Balachandran, Haribabu Jebiti, Yuki Imai, and Junpei Yuasa
[ 学会・会議名 ] 18th Asian Chemical Congress (18ACC) and 20th General Assembly of the Federation of Asian Chemical Societies
[ 発表日付 ] 2019年12月8日 ~ 12月12日
Design and Synthesis of Cyclometalated Iridium(III) Complexes Based on Post-Complexation Functionalization
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, C. Balachandran, Haribabu Jebiti, Abdullah-Al Masum, and Kana Naito
[ 学会・会議名 ] 3rd Acian Conference on Chemosensors and Imaging Probes (Asian ChIP-2019)
[ 発表日付 ] 2019年11月6日 ~ 11月9日
Design and Synthesis of Poly(2,2’-bipyridyl) Ligands and Controlled of Anticancer Activity by Metal Complexation.
[ 共同発表者名 ] Masumi Hirose, C. Balachandran, Zhu Jun Jie, and Shin Aoki
[ 学会・会議名 ] 7th Asian Congress on Coordination Chemistry (ACCC7).
[ 発表日付 ] 2019年10月15日 ~ 10月18日
Amphiphilic Cationic Triscyclometalated Iridium(III) Complex-Peptide Hybrids Induce Paraptosis-like Cell Death of Cancer Cells via Intracellular Ca2+-Dependent Pathway
[ 共同発表者名 ] Kenta Yokoi, C. Balachandran, and Shin Aoki
[ 学会・会議名 ] 7th Asian Congress on Coordination Chemistry (ACCC7)
[ 発表日付 ] 2019年10月15日 ~ 10月18日
Design and Synthesis of Cyclometalated Iridium(III) Complexes Functionalized with Peptides and Chromophores in Biomedical and Material Sciences.
[ 共同発表者名 ] 25. Shin Aoki, Kenta Yokoi, Kana Naito, C. Balachandran, Ayami Kazama, Junpei YuasaKuroda
[ 学会・会議名 ] The 69th meeting of the Complexation Society
[ 発表日付 ] 2019年9月21日 ~ 9月23日
Selective Substitution and Decomposition Reactions of Cyclometalated Iridium Complexes and Their Applications to Biomedical and Material Sciences.
[ 共同発表者名 ] Shin Aoki, Kenta Yokoi, Yuichi Tamura, Kana Naito, Ayami Kazama, C. Balachandran, Haribabu Jebiti, Junpei Yuasa, and Reiko Kurod
[ 学会・会議名 ] The 27th International Society of Heterocyclic Chemistry Congress (ISHC2019)
[ 発表日付 ] 2019年9月1日 ~ 9月6日
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