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Am80-Encapsulated Lipid Nanoparticles, Developed with the Aim of Achieving Alveolar Regeneration, Have an Improvement Effect on Pulmonary Emphysema
[ 全著者名 ] Tomomi Akita,Yuki Morita,Takehiro Kawai,Kazuaki Oda,Kota Tange,Yuta Nakai and Chikamasa Yamashita.
[ 掲載誌名 ] Pharmaceutics
[ 掲載年月 ] 2022年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Involvement of trigeminal axons in nose-to-brain delivery of glucagon-like peptide-2 derivative
[ 全著者名 ] Tomomi Akita, Yusuke Oda, Ryosuke Kimura, Mio Nagai, Ayano Tezuka, Mizuki Shimamura, Kaho Washizu, Jun-Ichiro Oka, Chikamasa Yamashita.
[ 掲載誌名 ] JOURNAL OF CONTROLLED RELEASE
[ 掲載年月 ] 2022年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
A Mouse Model for Tuberculosis Combined With Inhalable Imiquimod-PLGA Nanocomposite Particles Based on Macrophage Phenotype.
[ 全著者名 ] Teruki Nii, Shunsuke Takizawa, Tomomi Akita, Chikamasa Yamashita, Issei Takeuchi, Kimiko Makino.
[ 掲載誌名 ] in vivo
[ 掲載年月 ] 2022年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve β-amyloid peptide (25–35)-induced memory impairment in mice.
[ 全著者名 ] Junpei Takahashi, Yudai Ueta, Daisuke Yamada, Sachie Sasaki-Hamada, Takashi Iwai, Tomomi Akita, Chikamasa Yamashita, Akiyoshi Saitoh, Jun-Ichiro Oka.
[ 掲載誌名 ] Neuropsychopharmacology Reports
[ 掲載年月 ] 2022年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
吸入剤におけるTime-of-Flightの原理に基づく簡便な空気力学的粒度測定法に関する検討-多孔性粒子から構成される吸入剤への適用
[ 全著者名 ] 秋田智后、宮本佳保里、山下親正
[ 掲載誌名 ] 医薬品医療機器レギュラトリーサイエンス
[ 掲載年月 ] 2022年 4月
[ 著作区分 ] レフェリー付学術論文(日本語)
Radiolabeling Method for Lyophilizate for Dry Powder Inhalation Formulations.
[ 全著者名 ] Kahori Miyamoto, Tomomi Akita, and Chikamasa Yamashita.
[ 掲載誌名 ] Pharmaceutics
[ 掲載年月 ] 2022年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Clinical Study on Nicotinamide Phosphoribosyl Transferase and SIRT1 Level in Patients With Neutropenia After Chemotherapy for Lung Cancer.
[ 全著者名 ] Yukari Tsubata, Tomomi Akita, Ryosuke Tanino, Takamasa Hotta, Ayano Tezuka, Misato Kobayashi, Takae Okuno, Yohei Shiratsuki, Akari Tanino, Megumi Hamaguchi, Chikamasa Yamashita, Takeshi Isobe.
[ 掲載誌名 ] Shimane Journal of Medical Science.
[ 掲載年月 ] 2021年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Scale-up/tech transfer issues of the lyophilization cycle for biopharmaceuticals and recently emerging technologies and approaches.
[ 全著者名 ] Ryo Ohori, Tomomi Akita, Cikamasa Yamashita.
[ 掲載誌名 ] DRYING TECHNOLOGY
[ 掲載年月 ] 2021年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
凍結乾燥ケーキの品質に及ぼす凍結乾燥工程の一次乾燥時における昇温速度の影響
[ 全著者名 ] 大堀良、秋田智后、山下親正
[ 掲載誌名 ] 製剤機械技術学会誌 第119号
[ 掲載年月 ] 2021年 9月
[ 著作区分 ] レフェリー付学術論文(日本語)
Induction of mucosal immunity by pulmonary administration of a cell-targeting nanoparticle
[ 全著者名 ] Tomoaki Kurosaki, Yuki Katafuchi, Junya Hashizume, Hitomi Harasawa, Hiroo Nakagawa, Mikiro Nakashima, Tadahiro Nakamura, Chikamasa Yamashita, Hitoshi Sasaki & Yukinobu Kodama
[ 掲載誌名 ] DRUG DELIVERY
[ 掲載年月 ] 2021年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Usefulness of cell-penetrating peptides and penetration accelerating sequence for nose-to-brain delivery of glucagon-like peptide-2
[ 全著者名 ] Tomomi Akita, Ryosuke Kimura, Saki Akaguma, Mio Nagai, Yusuke Nakao, Mamiko Tsugane, Hiroaki Suzuki, Jun-ichiro Oka, Chikamasa Yamashita
[ 掲載誌名 ] JOURNAL OF CONTROLLED RELEASE
[ 掲載年月 ] 2021年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Optimization of Very Low-Dose Formulation of Vitamin D3 with Lyophilizate for Dry Powder Inhalation System by Simple Method Based on Time-of-Flight Theory
[ 全著者名 ] Kahori Miyamoto, Misato Yanagisawa, Hiroaki Taga, Hiromichi Yamaji, Tomomi Akita and Chikamasa Yamashita.
[ 掲載誌名 ] Pharmaceutics
[ 掲載年月 ] 2021年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Systemic Delivery of hGhrelin Derivative by Lyophilizate for Dry Powder Inhalation System in Monkeys.
[ 全著者名 ] Kahori Miyamoto, Yuko Ishibashi, Tomomi Akita and Chikamasa Yamashita.
[ 掲載誌名 ] Pharmaceutics
[ 掲載年月 ] 2021年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Investigation of lyophilized formulation susceptible to the ramp rate of shelf temperature in the primary drying process.
[ 全著者名 ] Ryo Ohori, Tomomi Akita, Cikamasa Yamashita.
[ 掲載誌名 ] JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
[ 掲載年月 ] 2021年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Simple Method to Measure the Aerodynamic Size Distribution of Porous Particles Generated on Lyophilizate for Dry Powder Inhalation.
[ 全著者名 ] Kahori Miyamoto, Hiroaki Taga, Tomomi Akita and Chikamasa Yamashita.
[ 掲載誌名 ] Pharmaceutics
[ 掲載年月 ] 2020年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Alveolar-Repairing Effect of 1α,25-Dihydroxyvitamin D3 on Chronic Obstructive Pulmonary Disease Mouse Model Based on Differentiation Inducing.
[ 全著者名 ] Tomomi Akita and Chikamasa Yamashita.
[ 掲載誌名 ] Journal of Cardiac and Pulmonary Rehabilitation.
[ 掲載年月 ] 2020年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Expression of clock gene Dbp in omental and mesenteric adipose tissue in patients with type 2 diabetes.
[ 全著者名 ] Kentaro Ushijima, Chisato Suzuki, Hiroko Kitamura, Ken Shimada, Hirotoshi Kawata, Akira Tanaka, Hisanaga Horie, Yoshinori Hosoya, Yasushi Imai, Chikamasa Yamashita, Akio Fujimura.
[ 掲載誌名 ] BMJ Open Diab Res Care
[ 掲載年月 ] 2020年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Development of a DNA Vaccine for Melanoma Metastasis by Inhalation Based on an Analysis of Transgene Expression Characteristics of Naked pDNA and a Ternary Complex in Mouse Lung Tissues.
[ 全著者名 ] Yukinobu Kodama, Mikiro Nakashima, Tadayuki Nagahara, Natsuko Oyama, Junya Hashizume, Hiroo Nakagawa, Hitomi Harasawa, Takahiro Muro, Tomoaki Kurosaki, Chikamasa Yamashita, Mitsuru Hashida, Takashi Kitahara, Hitoshi Sasaki, Shigeru Kawakami, Tadahiro Nakamura.
[ 掲載誌名 ] Pharmaceutics
[ 掲載年月 ] 2020年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
The effects of 1α,25-dihydroxyvitamin D3 on alveolar repair and bone mass in adiponectin-deficient mice.
[ 全著者名 ] Tomomi Akita, Mai Hirokawa, Chikamasa Yamashita.
[ 掲載誌名 ] JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
[ 掲載年月 ] 2020年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
A novel diagnostic system to evaluate epidermal growth factor receptor impact as a prognostic and therapeutic indicator for lung adenocarcinoma.
[ 全著者名 ] Kazuya Takakuwa, Kaoru Mogushi, Min Han, Tomoaki Fujii, Masaki Hosoya, Arina Yamanami, Tomomi Akita, Chikamasa Yamashita, Tetsu Hayashida, Shunsuke Kato, Shigeo Yamaguchi.
[ 掲載誌名 ] Scientific Reports
[ 掲載年月 ] 2020年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Efficient optimization of high-dose formulation of novel lyophilizates for dry powder inhalation by the combination of response surface methodology and time-of-flight measurement.
[ 全著者名 ] Ryo Ohori, Sakurako Kiuchi, Shintaro Sugiyama, Kahori Miyamoto, Tomomi Akita, Chikamasa Yamashita.
[ 掲載誌名 ] INTERNATIONAL JOURNAL OF PHARMACEUTICS
[ 掲載年月 ] 2020年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Method for Pulmonary Administration Using Negative Pressure Generated by Inspiration in Mice.
[ 全著者名 ] Yuki Oiso, Tomomi Akita, Daiki Kato, Chikamasa Yamashita.
[ 掲載誌名 ] pharmaceutics
[ 掲載年月 ] 2020年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Induction of Dbp by a histone deacetylase inhibitor is involved in amelioration of insulin sensitivity via adipocyte differentiation in ob/ob mice.
[ 全著者名 ] Chisato Suzuki, Kentaro Ushijima, Hitoshi Ando, Hiroko Kitamura, Michiko Horiguchi, Tomomi Akita, Chikamasa Yamashita, Akio Fujimura.
[ 掲載誌名 ] CHRONOBIOL INT
[ 掲載年月 ] 2019年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Mechanism of collapse of amorphous-based lyophilized cake induced by slow ramp during the shelf ramp process.
[ 全著者名 ] Ryo Ohori, Tomomi Akita, Chikamasa Yamashita.
[ 掲載誌名 ] INT J PHARMACEUT
[ 掲載年月 ] 2019年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
NAMPT Activity Before Cancer Chemotherapy may be Useful in Predicting Severe Neutropenia.
[ 全著者名 ] Yukari Tsubata, Ryosuke Tanino, Mika Nakao, Tamio Okimoto, Chikamasa Yamashita, Hiroshi Ohtsu, Takeshi Isobe.
[ 掲載誌名 ] International Journal of Experimental and Clinical Research.
[ 掲載年月 ] 2018年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Effect of temperature ramp rate during the primary drying process on the properties of amorphous-based lyophilized cake, Part 2: Successful lyophilization by adopting a fast ramp rate during primary drying in protein formulations.
[ 全著者名 ] RYO Ohori, Tomomi Akita, Chikamasa Yamashita.
[ 掲載誌名 ] EUR J PHARM BIOPHARM
[ 掲載年月 ] 2018年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Pulmonary administration of curcumin inhibits B16F10 melanomalung metastasis and invasion in mice.
[ 全著者名 ] Ken Shimada, Kentaro Ushijima, Chisato Suzuki, Michiko Horiguchi, Hitoshi Ando, Tomomi Akita, Mizuki Shimamura, Junki Fujii, Chikamasa Yamashita, Akio Fujimura.
[ 掲載誌名 ] CANCER CHEMOTH PHARM
[ 掲載年月 ] 2018年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma polyposis coli mutation in adult pancreatoblastoma
[ 全著者名 ] Shigeo Yamaguchi, Tomoaki Fujii, Yuki Izumi, Yuki Fukumura, Min Han,Hideki Yamaguchi, Tomomi Akita, Chikamasa Yamashita, Shunsuke Kato,Takao Sekiya
[ 掲載誌名 ] ONCOTARGET
[ 掲載年月 ] 2018年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Intranasal administration of neuromedin U derivatives containing cell-penetrating peptides and a penetration-accelerating sequence induced memory improvements in mice.
[ 全著者名 ] Sachie Sasaki-Hamada, Taichi Funane, Yusuke Nakao, Rie Sasaki, Mio Nagai, Yudai Ueta, Kazumi Yoshizawa, Michiko Horiguchi, Chikamasa Yamashita, Jun-Ichiro Oka
[ 掲載誌名 ] PEPTIDES
[ 掲載年月 ] 2018年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Dosing-time-dependent effect of rivaroxaban on coagulation activity in rats
[ 全著者名 ] Yuki Fujiwara,Hitoshi Ando,Kentaro Ushijima, Michiko Horiguchi, Chikamasa Yamashita, Akio Fujimura
[ 掲載誌名 ] J PHARMACOL SCI
[ 掲載年月 ] 2017年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
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