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Post-Complexation Functionalization of Cyclometalated Iridium(III) Complexes and Application to Biomedical and Material Sciences
[ 全著者名 ] Shin Aoki, Kenta Yokoi, Yosuke Hisamatsu, Chandrasekar Balachandran, Yuichi Tamura, and Tomohiro Tanaka
[ 掲載誌名 ] Topics in Current Chemistry
[ 掲載年月 ] 2022年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Design, Synthesis and Biological Evaluation of 2-Pyrrolone Derivatives as Radioprotectors
[ 全著者名 ] Hidetoshi Satoh, Shintaro Ochi, Kosuke Mizuno, Yutaka Saga, Shohei Ujita, Miyu Toyoda, Yuichi Nishiyama, Kasumi Tada, Yosuke Matsushita, Yuichi Deguchi, Keiji Suzuki, Yoshimasa Tanaka, Hiroshi Ueda, Toshiya Inaba, Yoshio Hosoi, Akinori Morita, Shin Aoki
[ 掲載誌名 ] Bioorganic & Medicinal Chemistry
[ 掲載年月 ] 2022年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Profiling Differntial Effects of Five Selective Serotonin Reuptake Inhibitors on TLRs-Dependent and -Indiependent IL-6 Production in Immune Cells Indentifies Fluoxetine as Preferred Antiinflammatory Drug Candidate
[ 全著者名 ] Yohei Takenaka, Ryu Tanaka, Kazuki Kitabatake, Kouji Kuramochi, Shin Aoki, and Mitsutoshi Tsukimoto
[ 掲載誌名 ] Frontiers in Pharmacology
[ 掲載年月 ] 2022年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Design, Synthesis, and Anticancer Activity of Triptycene-Peptide Hybrids that Induce Paraptotic Cell Death in Cancer Cells
[ 全著者名 ] Kohei Yamaguchi, Kenta Yokoi, Masakazu Umezawa, Koji Tsuchiya, Yasuyuki Yamada, and Shin Aoki
[ 掲載誌名 ] Bioconjugate Chemistry
[ 掲載年月 ] 2022年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Design, Synthesis of Spirooxiindole-Pyrrolidines Embedded with Indole and Pyridine Heterocycles by Multicomponent Reaction: Anticancer and In Silico Studies
[ 全著者名 ] Sivakali Mayakrishnan, Devarajan Kathirvelan, Yuvaraj Arun, Krishnan Saranraj, Chandrasekar Balachandran, Shin Aoki, Pannerselvam Yuvaraj, Narayanan Uma Maheswari
[ 掲載誌名 ] New Journal of Chemistry
[ 掲載年月 ] 2022年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Induction of Paraptosis by Cyclometalated Iridium Complex-Peptide Hybrids and CGP37157 via a Mitochondrial Ca2+ Overload Triggered by Membrane Fusion between Mitochondria and the Endoplasmic Reticulum
[ 全著者名 ] Kenta Yokoi, Kohei Yamaguchi, Masakazu Umezawa, Koji Tsuchiya, and Shin Aoki
[ 掲載誌名 ] Biochemistry
[ 掲載年月 ] 2022年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Potassium tert-Butoxide Promoted Intramolecular Mizoroki-Heck-Type Radical Cyclization: Photoluminescence Properties and Applications Live Cancer-Cell Imaging
[ 全著者名 ] Mahalingam Sivaraman, Sivakalai Mayakrishnan, Chandrasekar Balachandran, Shin Aoki, Narayanan Uma Maheswari, Paramasivan T. Perumal
[ 掲載誌名 ] Synlett
[ 掲載年月 ] 2022年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Effect of N-Benzyl Group in Indole Scaffold of Thiosemicarbazones on the Biological Activity of Their Pd(II) Complexes: DFT, Biomolecular Interaction, in Silico Docking, ADME and Cytotoxicity Studies
[ 全著者名 ] Nithya Balakrishnan, Jebiti Haribabu, Rahime Eshaghimalekshah, Srividya Swaminathan, Chandrasekar Balachandran, Nattamai S.P. Bhuvanesh, Shin Aoki, Ramasamy Karvembu
[ 掲載誌名 ] Inorganica Chimica Acta
[ 掲載年月 ] 2022年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Synthesis and Antiproliferative Activity of Novel Organometallic Cobalt(III) Complex Encapsulated in Polydiacetylene-Phospholipid Nanoformulation
[ 全著者名 ] Arangasamy Mounica, Chandrasekar Balachandran, Durairaj Gopalakrishnan, Pandiyan Sivasakthi, Muthuramalingam Prakash, Shin Aoki, Mani Ganeshpandian
[ 掲載誌名 ] Inorganica Chimicai Acta
[ 掲載年月 ] 2022年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Design, Synthesis and Biological Evaluation of Boron-Containing Macrocyclic Polyamine Dimers and Their Zinc(Ⅱ) Complexes for Boron Neutron Capture Therapy
[ 全著者名 ] Hiroki Ueda, Minoru Suzuki, Yoshinori Sakurai, Tomohiro Tanaka, and Shin Aoki
[ 掲載誌名 ] European Journal of Inorganic Chemistry
[ 掲載年月 ] 2021年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Post-complexation functionalizationによるシクロメタレート型イリジウム(III)錯体の機能化と生命科学および材料科学への応用―金属錯体をビルディングブロックとする機能性分子の創製― (Synthesis and Functionalization of Cyclometalated Iridium(III) Complexes by Post-Complexation Functionalization for Biomedical and Material Sciences -Development of Intelligent Molecules Using Metal Complex Building Blocks-)
[ 全著者名 ] 青木 伸、横井 健汰、Chandrasekar Balachandran、久松洋介 (Shin Aoki, Kenta Yokoi, Chandrasekar Balachandran, Yosuke Hisamatsu)
[ 掲載誌名 ] 有機合成化学協会誌 (Journal of Synthetic Organic Chemistry, Japan)
[ 掲載年月 ] 2021年 12月
[ 著作区分 ] レフェリー付学術論文(日本語)
Cyclometalated Iridium(III) Complex-Cationic Peptide Hybrids Trigger Paraptosis in Cancer Cells via Intracellular Ca2+ Overload from Endoplasmic Reticulum and a Decrease in a Mitochondrial Membrane Potential
[ 全著者名 ] Chandrasekar Balachandran, Kenta Yokoi, Kana Naito, Jebiti Haribabu, Yuichi Tamura, Masakazu Umezawa, Koji Tsuchiya, Toshitada Yoshihara, Seiji Tobita, and Shin Aoki
[ 掲載誌名 ] Molecules
[ 掲載年月 ] 2021年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Isohamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndorome
[ 全著者名 ] Yuichi Nishiyama, Akinori Morita, Shogo Tatsuta, Misaki Kanamaru, Masahiro Sakaue, Kenta Ueda, Manami Shono, Rie Fujita, Bing Wang, Yoshio Hosoi, Shin Aoki and Takeshi Sugai
[ 掲載誌名 ] Genes
[ 掲載年月 ] 2021年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA Intercalation Activity for Triggering a p53 Response, and Can Inhibit p53-Dependent Apoptosis
[ 全著者名 ] Akinori Morita, Shintaro Ochi, Hidetoshi Satoh, Shohei Ujita, Yosuke Matsushita, Kasumi Tada, Mihiro Toyoda, Yuichi Nishiyama, Kosuke Mizuno, Yuichi Deguchi, Keiji Suzuki, Yoshimasa Tanaka, Hiroshi Ueda, Toshiya Inaba, Yoshio Hosoi, and Shin Aoki
[ 掲載誌名 ] Life
[ 掲載年月 ] 2021年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Design, Synthesis and Biological Evaluation of Boron-Containing Macrocyclic Polyamines and Their Zinc(Ⅱ) Complexes for Boron Neutron Capture Therapy
[ 全著者名 ] Hiroki Ueda, Minoru Suzuki, Reiko Kuroda, Tomohiro Tanaka, and Shin Aoki,
[ 掲載誌名 ] Journal of Medicinal Chemistry
[ 掲載年月 ] 2021年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Evaluation of Sodium Orthovanadate as a Radioprotective Agent under Total-Body Irrdiation and Partial-Body Irradiation Conditions in Mice
[ 全著者名 ] Yuichi Nishiyama, Akinori Morita, Bing Wang, Takuma Sakai, Dwi Ramadhani, Hidetoshi Satoh, Kaoru Tanaka, Megumi Sasatani, Shintaro Ochi, Masahide Tominaga, Hitoshi Ikushima, Junji Ueno, Mitsuru Nenoi, and Shin Aoki,
[ 掲載誌名 ] International Journal of Radiation Biology
[ 掲載年月 ] 2021年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Rh(III)-catalysed Synthesis of Cinnolinium and Fluoranthenium Salts by Using C-H Activation/annulation Reactions: Organelle Specific Mitochondrial Staining Applications
[ 全著者名 ] Sivakali Mayakrishnan, Masilamani Tamizmani, Chandrasekar Balachandran, Shin Aoki, Uma Maheswari Narayanan
[ 掲載誌名 ] Organic & Biomolecular Chemistry
[ 掲載年月 ] 2021年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Synthesis and Anticancer Properties of Bis and Mono(cationic peptide) Hybrids of Cyclometalated Ir(III) Complexes: Effect of the Number of Peptide Units on Anticancer Activity
[ 全著者名 ] Haribabu Jebiti, Yuichi Tamura, Kenta Yokoi, Chandrasekar Balachandran, Masakazu Umezawa, Koji Tsuchiya, Yasuyuki Yamada, and Shin Aoki
[ 掲載誌名 ] European Journal of Inorganic Chemistry
[ 掲載年月 ] 2021年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Potential Anti-COVID-19 Agents, Cepharanthine and Nelfinavir, and Their Usage for Combination Treatment
[ 全著者名 ] Hirofumi Ohashi, Koichi Watashi, Wakana Saso, Kaho Shionoya, Shoya Iwanami, Takatsugu Hirokawa, Tsuyoshi Shirai, Shigehiko Kanaya, Yusuke Ito, Kwang Su Kim, Takao Nomura, Takeki Suzuki, Kazane Nishioka, Shuji Ando, Keisuke Ejima, Yoshiki Koizumi, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Tadaki Suzuki, Takao Hashiguchi, Katsumi Maenaka, Tetsuro Matano, Masamichi Muramatsu, Masayuki Saijo, Kazuyuki Aihara, Shingo Iwami, Makoto Takeda, Jane A. McKeating, and Takaji Wakita
[ 掲載誌名 ] iScience
[ 掲載年月 ] 2021年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Mefloquine, A Potent Anti-Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) Drug as An Entry Inhibitor in Vitro
[ 全著者名 ] Kaho Shionoya, Masako Yamasaki, Shoya Iwanami, Yusuke Ito, Shuetsu Fukushi, Hirofumi Ohashi, Wakana Saso, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Shingo Iwami, Yoshimasa Takahashi, Tadaki Suzuki, Masamichi Muramatsu, Shutoku Matsuyama, Makoto Takeda, Takaji Wakita, Koichi Watashi
[ 掲載誌名 ] Frontiers in Microbiology
[ 掲載年月 ] 2021年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Development of Metallosupramolecular Phosphatases Based on Combinatorial Self-Assembly of Metal Complexes and Organic Building Blocks for Catalytic Hydrolysis of Phosphate Monoesters
[ 全著者名 ] Shin Aoki, Akib Bin Rahman, Yosuke Hisamatsu, Yuya Miyazawa, Mohd Zulkefeli, Yuaka Saga, and Tomohiro Tanaka
[ 掲載誌名 ] Results in Chemistry (a joint special issue with Inorganica Chimica Acta)
[ 掲載年月 ] 2021年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Design and Synthesis of Supramolecular Phosphatases Formed from a Bis(Zn2+-Cyclen) Complex, Barbital-Crown-K+ Conjugate and Cu2+ for the Catalytic Hydrolysis of Phosphate Monoester
[ 全著者名 ] Akib Bin Rahman, Hirokazu Okamoto, Yuya Miyazawa, and Shin Aoki
[ 掲載誌名 ] European Journal of Inorganic Chemistry
[ 掲載年月 ] 2021年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
理科大の化学と生物学の研究力を活かした新型コロナウイルス治療薬の開発
[ 全著者名 ] 倉持幸司、渡士幸一、大橋啓史、青木伸、田中智博
[ 掲載誌名 ] 理大科学フォーラム
[ 掲載年月 ] 2021年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Protective Effects of p53 Regulatory Agents against High-LET Radiation-Induced Injury in Mice
[ 全著者名 ] Akinori Morita, Bing Wang, Kaoru Tanaka, Takanori Katsube, Masahiro Murakami, Takashi Shimokawa, Yuichi Nishiyama, Shintaro Ochi, Hidetoshi Satoh, Mitsuru Nenoi and Shin Aoki
[ 掲載誌名 ] Frontiers in Public Health
[ 掲載年月 ] 2020年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Synthesis, Anticancer and Molecular Docking Studies of New class of Benzoisoxazolyl-piperidinyl-1,2,3-triazoles
[ 全著者名 ] Govindhan Muniyappan, Subramanian Kathavarayan, Chandrasekar Balachandran, Easwaramoorthi Kalliyappan, Sakkarapalayam M. Mahalingam, Abdul Ajees Abdul Salam, Shin Aoki
[ 掲載誌名 ] The Journal of King Saud University-Science
[ 掲載年月 ] 2020年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
N-substitution in isatin thiosemicarbazones decides nuclearity of Cu(II) complexes – Spectroscopic, molecular docking and cytotoxic studies
[ 全著者名 ] Haribabu Jebiti, Othman Ibrahim Alajrawy, Kumaramangalam Jeyelakshmi, Chandrasekar Balachandran, Dhanabalan Anantha Krishnan, Nattamal Bhuvanesh, Shin Aoki, and Natarajan Karuppannan, Ramasamy Karvembu
[ 掲載誌名 ] Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
[ 掲載年月 ] 2020年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Synthesis, Characterization, Theoretical, Molecular Docking and in Vitro Biological Activity Studies of Ru(II) (eta-6-p-Cymene) Complexes with Novel Aniline Substituted Aroyl Selenoureas
[ 全著者名 ] Moideen Musthafa, Ramaiah Konakanchi, Rakesh Ganguly, Chandrasekar Balachandran, Shin Aoki, Anandaram Sreekanth,
[ 掲載誌名 ] Journal of Biomolecular Structure and Dynamics
[ 掲載年月 ] 2020年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Amphiphilic Cationic Triscyclometalated Iridium(III) Complex-Peptide Hybrids Induce Paraptosis-like Cell Death of Cancer Cells via an Intracellular Ca2+-Dependent Pathway
[ 全著者名 ] Kenta Yokoi, Chandrasekar Balachandran, Masakazu Umezawa, Koji Tsuchiya, Aleksandra Mitrić and Shin Aoki
[ 掲載誌名 ] ACS Omega
[ 掲載年月 ] 2020年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Design and Synthesis of Cyclometalated Iridium(III) Complex-Chromophore Hybrids that Exhibit Long-Emission Lifetimes Based on a Reversible Electronic Energy Transfer Mechanism
[ 全著者名 ] Ayami Kazama, Yuki Imai, Yoshinori Okayasu, Yasuyuki Yamada, Junpei Yuasa, and Shin Aoki
[ 掲載誌名 ] Inorganic Chemistry
[ 掲載年月 ] 2020年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
ROS-Responsive Chitosan Coated Magnetic Iron Oxide Nanoparticles as Potential Vehicles for Targeted Drug Delivery in Cancer Therapy
[ 全著者名 ] Srinivasan Ayyanaar, Chandrasekar Balachandran, Rangaswamy Chinnabba Bhaskar, Mookkandi Palsamy Kesavan, Shin Aoki, Ramachandran Palpandi Raja, Jegathalaprathaban Rajesh, Thomas J. Webster, and Gurusamy Rajagopal
[ 掲載誌名 ] International Journal of Nanomedicine
[ 掲載年月 ] 2020年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
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