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Isomerization of E‑Cinnamamides into Z‑Cinnamamides Using a Recycling Photoreactor
[ 全著者名 ] Mayuko Suga, Saki Fukushima, Kosho Makino, Kayo Nakamura, Hidetsugu Tabata, Tetsuta Oshitari, Hideaki Natsugari, Noritaka Kuroda, Kunio Kanemaru, Yuji Oda, and Hideyo Takahashi
[ 掲載誌名 ] JOURNAL OF ORGANIC CHEMISTRY
[ 掲載年月 ] 2024年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Fentanyl Analogs Exert Antinociceptive Effects via Sodium Channel Blockade in Mice
[ 全著者名 ] Satoka Kasai, Natsuki Ogawa, Miho Takagi, Yukino Takahashi, Kosho Makino, Hironobu Arita, Hideyo Takahashi, Kazumi Yoshizawa
[ 掲載誌名 ] Biological and Pharmaceutical Bulletin
[ 掲載年月 ] 2024年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Drugs possessing aryloxypropanamine pharmacophore, duloxetine, dapoxetine and propranolol, increase allopregnanolone in rat brain: Possible involvement of allopregnanolone in their central nervous system effects
[ 全著者名 ] Nishimoto-Kusunose, Shoichi; Hirakawa, Ayaka; Tanaka, Asuka; Yoshizawa, Kazumi; Makino, Kosho; Takahashi, Hideyo; Higashi, Tatsuya
[ 掲載誌名 ] STEROIDS
[ 掲載年月 ] 2023年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Physiologically based pharmacokinetic model analysis of the inhibitory effect of vonoprazan on the metabolic activation of proguanil
[ 全著者名 ] Okubo, Kenjiro; Kudo, Toshiyuki; Yoshihara, Sae; Nakabayashi, Yu; Nakauchi, Kana; Tanaka, Akimi; Saito, Moe; Tsujisawa, Ayumi; Goda, Hitomi; Yamagishi, Yoshiaki; Otake, Chinatsu; Makino, Kosho ; Takahashi, Hideyo ; Ito, Kiyomi
[ 掲載誌名 ] Drug Metabolism and Pharmacokinetics
[ 掲載年月 ] 2023年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Stereochemistry of N-Acyl-5H-dibenzo[b,d]azepin-7(6H)-ones
[ 全著者名 ] Chiba, Arisa; Tanaka, Ryoko; Hotta, Mayuno; Nakamura, Kayo; Makino, Kosho; Tabata, Hidetsugu; Oshitari, Tetsuta; Natsugari, Hideaki; Takahashi, Hideyo
[ 掲載誌名 ] MOLECULES
[ 掲載年月 ] 2023年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Conversion of racemic alkyl aryl sulfoxides into pure enantiomers using a recycle photoreator: Tandem use of chromatography on chiral support and photoracemization on solid support.
[ 全著者名 ] Tozawa, Kumi; Makino, Kosho; Tanaka, Yuki; Nakamura, Kayo; Inagaki, Akiko; Tabata, Hidetsugu ; Oshitari, Tetsuta ; Natsugari, Hideaki ; Kuroda, Noritaka; Kanemaru, Kunio; Oda, Yuji; Takahashi, Hideyo
[ 掲載誌名 ] JOURNAL OF ORGANIC CHEMISTRY
[ 掲載年月 ] 2023年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Stereochemical Analysis of Trifluoroacetamide Derivatives Based on Through-Space1H-19F Spin-Spin Couplings
[ 全著者名 ] Li, Yan; Ohtake, Chinatsu; Hotta, Mayuno; Tabata, Hidetsugu ; Hirano, Kiriko; Iida, Motoo; Nakamura, Kayo; Makino, Kosho; Oshitari, Tetsuta ; Natsugari, Hideaki ; Kusumi, Takenori; Takahashi, Hideyo
[ 掲載誌名 ] JOURNAL OF ORGANIC CHEMISTRY
[ 掲載年月 ] 2023年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
科学的かつ客観的な視点からの医薬品情報収集・吟味の重要性に関する調査研究
[ 全著者名 ] 高島佳央理,青山隆夫,小茂田昌代,斎藤顕宜,高橋秀依,西川元也,嶋田修治,鈴木立紀,真野泰成,高澤涼子
[ 掲載誌名 ] 臨床薬理
[ 掲載年月 ] 2023年 5月
[ 著作区分 ] レフェリー付学術論文(日本語)
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
[ 全著者名 ] Nakamura, Mari; Hojo, Motoki; Kawai, Ayaka; Ikushima, Kiyomi; Nagasawa, Akemichi; Takahashi, Hideyo; Makino, Kosho; Suzuki, Toshinari; Suzuki, Jin; Inomata, Akiko
[ 掲載誌名 ] Fundamental Toxicological Sciences
[ 掲載年月 ] 2023年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
Cytotoxic effects of psychoactive isobutyrylfentanyl and its halogenated derivatives on isolated rat hepatocytes
[ 全著者名 ] Nakagawa, Yoshio ; Suzuki, Jin; Suzuki, Toshinari; Takahashi, Hideyo; Makino, Kosho; Ono, Yasushi; Sakamoto, Miho; Inomata, Akiko
[ 掲載誌名 ] JOURNAL OF APPLIED TOXICOLOGY
[ 掲載年月 ] 2023年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Hepatic and renal toxicities and metabolism of fentanyl analogues in rats
[ 全著者名 ] Yasushi Ono, Miho Sakamoto, Kosho Makino, Kuniaki Tayama, Yukie Tada, Yoshio Nakagawa, Jun’ichi Nakajima, Jin Suzuki, Toshinari Suzuki, Hideyo Takahashi, Akiko Inomata & Takako Moriyasu
[ 掲載誌名 ] NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
[ 掲載年月 ] 2023年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Atropodiastereoselective 5N-Acylation of 1,5-Benzodiazepin-2-ones with (S)-2-Phenylpropanoyl and (S)-2-Phenylbutanoyl Chlorides
[ 全著者名 ] Funaki, Kaoru; Tabata, Hidetsugu ; Nakazato, Yusuke; Takahashi, Yuka; Tasaka, Tomohiko; Takahashi, Hideyo ; Natsugari, Hideaki ; Oshitari, Tetsuta
[ 掲載誌名 ] JOURNAL OF ORGANIC CHEMISTRY
[ 掲載年月 ] 2022年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Trajectory of the spectral/structural rearrangements for photo-oxidative reaction of neat ketoprofen and its cyclodextrin complex
[ 全著者名 ] Ryosuke Hiroshige, Satoru Goto, Chihiro Tsunoda, Risa Ichii, Shota Shimizu, Yuta Otsuka, Kosho Makino, Hideyo Takahashi, Hideshi Yokoyama
[ 掲載誌名 ] JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
[ 掲載年月 ] 2022年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Axial chirality and affinity at the GABAA receptor of triazolobenzodiazepines
[ 全著者名 ] Tanaka, Ryoko; Makino, Kosho; Tabata, Hidetsugu; Oshitari, Tetsuta; Natsugari, Hideaki; Takahashi, Hideyo
[ 掲載誌名 ] BIOORGANIC & MEDICINAL CHEMISTRY
[ 掲載年月 ] 2022年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Disulfiram produces potent anxiolytic-like effects without benzodiazepines anxiolytics-related adverse effects in mice
[ 全著者名 ] Akiyoshi Saitoh, Yoshifumi Nagayama, Daisuke Yamada, Kosho Makino, Toshinori Yoshioka, Nanami Yamanaka, Momoka Nakatani, Yoshino Takahashi, Mayuna Yamazaki, Chihiro Shigemoto, Misaki Ohashi, Kotaro Okano,Tomoki Omata, Etusko Toda, Yoshitake Sano, Hideyo Takahashi, Kouji Matsushima, Yuya Terashima
[ 掲載誌名 ] Frontiers in Pharmacology
[ 掲載年月 ] 2022年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Protective effects of cyclodextrins on edaravone degradation induced by atmospheric oxygen or additive oxidant
[ 全著者名 ] Ryosuke Hiroshige; Satoru Goto; Risa Ichii; Shota Shimizu; Ayako Wada-Hirai; Ying-Peng Li; Yohsuke Shimada; Yuta Otsuka; Kosho Makino; Hideyo Takahashi;
[ 掲載誌名 ] JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
[ 掲載年月 ] 2022年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Photoisomerization of Sulindac and Ozagrel hydrochloride by Vitamin B2 catalyst under visible light irradiation
[ 全著者名 ] Mayuko Suga, Kosho Makino, Hidetsugu Tabata, Tetsuta, Oshitari, Hideaki Natsugari, Hideyo Takahashi
[ 掲載誌名 ] PHARMACEUTICAL RESEARCH
[ 掲載年月 ] 2022年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Atropisomeric properties of N-alkyl/aryl 5H-dibenz[b,f]azepines
[ 全著者名 ] Tanaka, Ryoko; Nabae, Ayana; Yamane, Koki; Makino, Kosho; Tabata, Hidetsugu; Oshitari, Tetsuta; Natsugari, Hideaki; Takahashi, Hideyo
[ 掲載誌名 ] CHEMICAL & PHARMACEUTICAL BULLETIN
[ 掲載年月 ] 2022年
[ 著作区分 ] レフェリー付学術論文(外国語)
Academic detailing exercise course in RIKADAI: Toward the integration of basic and clinical science
[ 全著者名 ] Hideyo Takahashi, Takao Aoyama, Akiyoshi Saitoh, Shuji Shimada, Tatsunori Suzuki, Ryoko Takasawa, Makiya Nishikawa, Yasunari Mano, Masayo Komoda
[ 掲載誌名 ] Journal of Asian Association of Schools of Pharmacy
[ 掲載年月 ] 2021年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Rapid photoracemization of chiral alkyl aryl sulfoxides
[ 全著者名 ] Makino Kosho, Tozawa Kumi, Tanaka Yuki, Inagaki Akiko, Tabata Hidetsugu, Oshitari Tetsuta, Natsugari Hideaki, Takahashi Hideyo
[ 掲載誌名 ] JOURNAL OF ORGANIC CHEMISTRY
[ 掲載年月 ] 2021年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Singular value decomposition analysis of the secondary structure features contributing to the circular dichroism spectra of model proteins
[ 全著者名 ] Tomoki Shiratori, Satoru Goto, Tomoya Sekiguchi, Takahiro Kasai, Yuta Otsuka, Kyouhei Higashi, Kosho Makino, Hideyo Takahashi, Kazushi Komatsu
[ 掲載誌名 ] Biochemistry and Biophysics Reports
[ 掲載年月 ] 2021年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Experimental study of the Raman spectra of imine emulsification with chemometrics
[ 全著者名 ] Yuta Otsuka, Kosho Makino, Hideyo Takahashi
[ 掲載誌名 ] Journal of Oleo Science
[ 掲載年月 ] 2021年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Atropisomeric Properties of 9-Methyl-1,4-benzodiazepin-2-ones
[ 全著者名 ] Tanaka, Ryoko; Makino, Kosho; Tabata, Hidetsugu; Oshitari, Tetsuta; Natsugari, Hideaki; Takahashi, Hideyo
[ 掲載誌名 ] SYNTHESIS-STUTTGART
[ 掲載年月 ] 2021年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Pharmacokinetics of CuGTSM, a novel drug candidate, in a mouse model of Menkes disease.
[ 全著者名 ] Yamagishi, Yoshiaki; Kudo, Toshiyuki; Oyumi, Masafumi; Sakamoto, Yusuke; Takahashi, Kazuki; Akashi, Taiki; Kobayashi, Shohei; Kawakami, Takeaki; Goda, Hitomi; Sato, Yasuhiro; Mimaki, Masakazu; Kodama, Hiroko; Munakata, Mitsutoshi; Makino, Kosho; Takahashi, Hideyo; Fukami, Toshiro; Ito, Kiyomi
[ 掲載誌名 ] PHARMACEUTICAL RESEARCH
[ 掲載年月 ] 2021年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Atropisomeric Properties of N-​Acyl​/N-​Sulfonyl 5H-​Dibenzo[b,​d]​azepin-​7(6H)​-​ones
[ 全著者名 ] Namba, Takuya; Hotta, Mayuno; Tabata, Hidetsugu; Makino, Kosho; Oshitari, Tetsuta; Natsugari, Hideaki; Takahashi, Hideyo
[ 掲載誌名 ] JOURNAL OF ORGANIC CHEMISTRY
[ 掲載年月 ] 2021年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Differences in the antinociceptive effects of serotonin-noradrenaline reuptake inhibitors via sodium channel blockade using the veratrine test in mice
[ 全著者名 ] Kazumi Yoshizawa, Yukina Suzuki, Toka Nakamura, Yukino Takahashi, Kosho Makino, Hideyo Takahashi
[ 掲載誌名 ] NEUROREPORT
[ 掲載年月 ] 2021年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Conformational Preference of 2'-​Fluoro-​Substituted Acetophenone Derivatives Revealed by Through-​Space 1H-​19F and 13C-​19F Spin-​Spin Couplings
[ 全著者名 ] Otake, Chinatsu; Namba, Takuya; Tabata, Hidetsugu; Makino, Kosho; Hirano, Kiriko; Oshitari, Tetsuta; Natsugari, Hideaki; Kusumi, Takenori; Takahashi, Hideyo
[ 掲載誌名 ] JOURNAL OF ORGANIC CHEMISTRY
[ 掲載年月 ] 2021年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Transcriptional induction of cystathionine γ-​lyase, a reactive sulfur-​producing enzyme, by copper diethyldithiocarbamate in cultured vascular endothelial cells
[ 全著者名 ] Fujie, Tomoya; Takahashi, Akane; Takahashi, Musubu; Hara, Takato; Soyama, Asuka; Makino, Kosho; Takahashi, Hideyo; Yamamoto, Chika; Kumagai, Yoshito; Naka, Hiroshi; Kaji, Toshiyuki
[ 掲載誌名 ] INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
[ 掲載年月 ] 2020年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Structural basis of beneficial design for effective nicotinamide phosphoribosyltransferase inhibitors
[ 全著者名 ] Sei-ichi Tanuma, Kiyotaka Katsuragi, Tkahiro Oyama, Atsushi Yoshimori, Yuri Shibasaki, Yasunobu Asawa, Hiroaki Yamazaki, Kosho Makino, Miwa Okazawa, Yoko Ogino、Yoshimi, Sakamoto, Miyuki Nomura, Akira Sato, Hideaki Abe, Hiroyuki Nakamura, Hideyo Takahahi, Nobuhiro Tanuma, Fumiaki Uchiumi
[ 掲載誌名 ] Molecules
[ 掲載年月 ] 2020年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Conformational properties and M1 antimuscarinic activity of 4-substituted pirenzepine /telenzepine analogues
[ 全著者名 ] Kanase Yuki, Makino Kosho, Yoshinaga Takashi, Tabata Hidetsugu, Oshitari Tetsuta, Natsugari Hideaki, Takahashi Hideyo
[ 掲載誌名 ] Heterocycles
[ 掲載年月 ] 2020年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
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