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Epidermal loss of Bcl6 exacerbates MC903-induced atopic dermatitis-like skin inflammation
[ 全著者名 ] Kaori Kanemaru, Kento Nagasawa, Yuta Kunugi, Asahi Tanaka, Shunsuke Ikeoku, Yuki Tai, Yohsuke Harada, Yoshikazu Nakamura
[ 掲載誌名 ] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
[ 掲載年月 ] 2024年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3
[ 全著者名 ] Roser Tachó-Piñot, Christopher T. Stamper, James I. King, Veronika Matei-Rascu, Erin Richardson, Zhi Li, Luke B. Roberts, John W. Bassett, Felipe Melo-Gonzalez, Rémi Fiancette, I-Hsuan Lin, Alexander Dent, Yohsuke Harada, Conor Finlay, Jenny Mjösberg, David R. Withers, Matthew R. Hepworth.
[ 掲載誌名 ] Cell Reports
[ 掲載年月 ] 2023年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
High expression of PKCλ and ALDH1A3 indicates a poor prognosis, and PKCλ is required for the asymmetric cell division of ALDH1A3-positive cancer stem cells in PDAC
[ 全著者名 ] Takahiro Kasai, Shoma Tamori, Yuta Takasaki, Izumi Matsuoka, Ayaka Ozaki, Chika Matsuda, Yohsuke Harada, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto
[ 掲載誌名 ] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
[ 掲載年月 ] 2023年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
High SLC20A1 Expression Indicates Poor Prognosis in Prostate Cancer
[ 全著者名 ] OKAMOTO TAIKI, ONAGA CHOTARO, MATSUOKA IZUMI, OZAKI AYAKA, MATSUDA CHIKA, KASAI TAKAHIRO, XIONG YUYUN, HARADA YOHSUKE, SATO TSUGUMICHI, NAKANO YOSHIO,MANO YASUNARI, MIYAZAKI SATORU, ISHIGURO HITOSHI, SATO KEIKO, TAMORI SHOMA, SASAKI KAZUNORI, OHNO SHIGEO, and AKIMOTO KAZUNORI
[ 掲載誌名 ] Cancer Diagnosis & Prognosis
[ 掲載年月 ] 2023年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Spatiotemporal resolution of germinal center Tfh cell differentiation and divergence from central memory CD4+ T cell fate
[ 全著者名 ] Fangming Zhu, Ryan J. McMonigle, Andrew R. Schroeder, Xianyou Xia, David Figge, Braxton D. Greer, Edahí González-Avalos, Diego O. Sialer, Yin-Hu Wang, Kelly M. Chandler, Adam J. Getzler, Emily R. Brown, Changchun Xiao, Olaf Kutsch, Yohsuke Harada, Matthew E. Pipkin & Hui Hu
[ 掲載誌名 ] Nature Communications
[ 掲載年月 ] 2023年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Foxp3 and Bcl6 deficiency synergistically induces spontaneous development of atopic dermatitis-like skin disease
[ 全著者名 ] Yuki Tai, Yuki Sakaida, Riyo Kawasaki, Kaori Kanemaru, Kazunori Akimoto, Frank Brombacher, Shuhei Ogawa, Yoshikazu Nakamura, Yohsuke Harada
[ 掲載誌名 ] INTERNATIONAL IMMUNOLOGY
[ 掲載年月 ] 2023年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Dysfunction of Foxp3+ Regulatory T Cells Induces Dysbiosis of Gut Microbiota via Aberrant Binding of Immunoglobulins to Microbes in the Intestinal Lumen
[ 全著者名 ] Kouhei Koshida, Mitsuki Ito, Kyosuke Yakabe, Yoshimitsu Takahashi, Yuki Ta, Ryouhei Akasako, Tatsuki Kimizuka, Shunsuke Takano, Natsumi Sakamoto, Kei Haniuda, Shuhei Ogawa, Shunsuke Kimura, Yun-Gi Kim, Koji Hase, and Yohsuke Harada
[ 掲載誌名 ] INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
[ 掲載年月 ] 2023年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
High Expression of CD58 and ALDH1A3 Predicts a Poor Prognosis in Basal-like Breast Cancer
[ 全著者名 ] YUYUN XIONG, HITOMI MOTOMURA, SHOMA TAMORI, AYAKA OZAKI, CHOTARO ONAGA, YASUSHI HARA, KEIKO SATO, KOUJI TAHATA, YOHSUKE HARADA, KAZUNORI SASAKI, YUN-WEN ZHENG, SHIGEO OHNO and KAZUNORI AKIMOTO
[ 掲載誌名 ] ANTICANCER RESEARCH
[ 掲載年月 ] 2022年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
High Expression of p62 and ALDH1A3 Is Associated With Poor Prognosis in Luminal B Breast Cancer
[ 全著者名 ] AYAKA OZAKI, HITOMI MOTOMURA, SHOMA TAMORI, CHOTARO ONAGA, YUKA NAGASHIMA, MAHO KOTORI, CHIKA MATSUDA, AKARI MATSUDA, NANAKO MOCHIZUKI, TSUGUMICHI SATO, YASUSHI HARA, KEIKO SATO, YOHEI MIYAGI, YOJI NAGASHIMA, TAKEHISA HANAWA, YOHSUKE HARADA, YUYUN XIONG, KAZUNORI SASAKI, SHIGEO OHNO and KAZUNORI AKIMOTO
[ 掲載誌名 ] ANTICANCER RESEARCH
[ 掲載年月 ] 2022年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Gasdermin D–mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma
[ 全著者名 ] Yamagishi R, Kamachi F, Nakamura M, Yamazaki S, Kamiya T, Takasugi M, Cheng Y, Nonaka Y, Yukawa-Muto Y, Thuy LTT, Harada Y, Arai T, Loo TM, Yoshimoto S, Ando T, Nakajima M, Taguchi H, Ishikawa T, Akiba H, Miyake S, Kubo M, Iwakura Y, Fukuda S, Chen WY, Kawada N, Rudensky A, Nakae S, Hara E, Ohtani N.
[ 掲載誌名 ] Science Immunology
[ 掲載年月 ] 2022年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival
[ 全著者名 ] HITOMI MOTOMURA, SHOMA TAMORI, MASA-AKI YATANI, AYANO NAMIKI, CHOTARO ONAGA, AYAKA OZAKI, RYOKO TAKASAWA, YASUNARI MANO, TSUGUMICHI SATO, YASUSHI HARA, KEIKO SATO, XIONG YUYUN, YOHSUKE HARADA, TAKEHISA HANAWA, SEI-ICHI TANUMA, KAZUNORI SASAKI, SHIGEO OHNO and KAZUNORI AKIMOTO
[ 掲載誌名 ] ANTICANCER RESEARCH
[ 掲載年月 ] 2021年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers
[ 全著者名 ] CHOTARO ONAGA, SHOMA TAMORI, HITOMI MOTOMURA, AYAKA OZAKI, CHIKA MATSUDA, IZUMI MATSUOKA, TAKUMA FUJITA, YUKA NOZAKI, YASUSHI HARA, YOHEI KAWANO, YOHSUKE HARADA, TSUGUMICHI SATO, YASUNARI MANO, KEIKO SATO, and KAZUNORI AKIMOTO
[ 掲載誌名 ] ANTICANCER RESEARCH
[ 掲載年月 ] 2021年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells.
[ 全著者名 ] Takahashi D, Hoshina N, Kabumoto Y, Maeda Y, Suzuki A, Tanabe H, Isobe J, Yamada T, Muroi K, Yanagisawa Y, Nakamura A, Fujimura Y, Saeki A, Ueda M, Matsumoto R, Asaoka H, Clarke JM, Harada Y, Umemoto E, Komatsu N, Okada T, Takayanagi H, Takeda K, Tomura M, Hase K.
[ 掲載誌名 ] EBioMedicine
[ 掲載年月 ] 2020年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Spontaneous antibody production caused by regulatory T cell deficiency occurs through a germinal center-independent pathway
[ 全著者名 ] Yuki Tai, Azumi Takano, Katsura Haga, Kouhei Koshida, Yohsuke Harada
[ 掲載誌名 ] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
[ 掲載年月 ] 2020年 5月
[ 著作区分 ] レフェリー付学術論文(外国語)
High Expression of c-Met , PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer
[ 全著者名 ] HITOMI MOTOMURA, YUKA NOZAKI, CHOTARO ONAGA, AYAKA OZAKI, SHOMA TAMORI, TAKA-AKI SHIINA, SHOTARO KANAI, CHIHIRO OHIRA, YASUSHI HARA, YOHSUKE HARADA, RYOKO TAKASAWA, TAKEHISA HANAWA, SEI-ICHI TANUMA, YASUNARI MANO, TSUGUMICHI SATO, KEIKO SATO and KAZUNORI AKIMOTO
[ 掲載誌名 ] ANTICANCER RESEARCH
[ 掲載年月 ] 2020年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Dysregulation of humoral immunity in Foxp3 conditional-knockout mice
[ 全著者名 ] Yuki Tai, Kazuki Sakamoto, Azumi Takano, Katsura Haga, Yohsuke Harada
[ 掲載誌名 ] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
[ 掲載年月 ] 2019年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
A novel mouse model for tracking the fate of CXCR5-expressing T cells.
[ 全著者名 ] Takebe T, Sakamoto K, Higami Y, Harada Y.
[ 掲載誌名 ] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
[ 掲載年月 ] 2017年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.
[ 全著者名 ] Kunitake Higo, Masayuki Oda, Hisayuki Morii, Jun Takahashi, Yohsuke Harada, Shuhei Ogawa, and Ryo Abe
[ 掲載誌名 ] IMMUNOLOGICAL INVESTIGATIONS
[ 掲載年月 ] 2014年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells.
[ 全著者名 ] Harada Y, Tanaka S, Motomura Y, Harada Y, Ohno S, Ohno S, Yanagi Y, Inoue H, Kubo M.
[ 掲載誌名 ] IMMUNITY
[ 掲載年月 ] 2012年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells.
[ 全著者名 ] Harada Y, Harada Y, Elly C, Ying G, Paik JH, Depinho RA, Liu YC.
[ 掲載誌名 ] JOURNAL OF EXPERIMENTAL MEDICINE
[ 掲載年月 ] 2010年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1.
[ 全著者名 ] Kojo S, Elly C, Harada Y, Langdon WY, Kronenberg M, Liu YC.
[ 掲載誌名 ] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
[ 掲載年月 ] 2009年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
Palmitoylation-dependent plasma membrane transport, but lipid raftindependentsignaling by linker for activation of T cells (LAT).
[ 全著者名 ] Hundt M, Harada Y, De Giorgio L, Tanimura N, Zhang W, Altman A.
[ 掲載誌名 ] JOURNAL OF IMMUNOLOGY
[ 掲載年月 ] 2009年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis.
[ 全著者名 ] Takeda K, Harada Y, Watanabe R, Inutake Y, Ogawa S, Onuki K, Kagaya S, Tanabe K, Kishimoto H, Abe R.
[ 掲載誌名 ] INTERNATIONAL IMMUNOLOGY
[ 掲載年月 ] 2008年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1.
[ 全著者名 ] Venuprasad K, Huang H, Harada Y, Elly C, Subramaniam M, Spelsberg T, Su J, Liu YC.
[ 掲載誌名 ] NATURE IMMUNOLOGY
[ 掲載年月 ] 2008年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation.
[ 全著者名 ] Watanabe R, Harada Y, Takeda K, Takahashi J, Ohnuki K, Ogawa S, Ohgai D, Kaibara N, Koiwai O, Tanabe K, Toma H, Sugamura K, Abe R.
[ 掲載誌名 ] JOURNAL OF IMMUNOLOGY
[ 掲載年月 ] 2006年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation.
[ 全著者名 ] Venuprasad K, Elly C, Gao M, Salek-Ardakani S, Harada Y, Luo JL, Yang C, Croft M, Inoue K, Karin M, Liu YC.
[ 掲載誌名 ] JOURNAL OF CLINICAL INVESTIGATION
[ 掲載年月 ] 2006年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation.
[ 全著者名 ] Yang C, Zhou W, Jeon MS, Demydenko D, Harada Y, Zhou H, Liu YC.
[ 掲載誌名 ] MOLECULAR CELL
[ 掲載年月 ] 2006年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Immune regulation by ubiquitin conjugation.
[ 全著者名 ] Venuprasad K, Yang C, Shao Y, Demydenko D, Harada Y, Jeon MS, Liu YC.
[ 掲載誌名 ] Advances in Experimental Medicine and Biology
[ 掲載年月 ] 2006年
[ 著作区分 ] レフェリー付学術論文(外国語)
Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint.
[ 全著者名 ] Williams JA, Hathcock KS, Klug D, Harada Y, Choudhury B, Allison JP, Abe R, Hodes RJ.
[ 掲載誌名 ] JOURNAL OF IMMUNOLOGY
[ 掲載年月 ] 2005年 10月
[ 著作区分 ] レフェリー付学術論文(外国語)
ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling.
[ 全著者名 ] Watanabe M, Watanabe S, Hara Y, Harada Y, Kubo M, Tanabe K, Toma H, Abe R.
[ 掲載誌名 ] JOURNAL OF IMMUNOLOGY
[ 掲載年月 ] 2005年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
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