東京理科大学　研究者情報データベース　

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Transcriptome analysis of cultured human vascular endothelial cells after γ-ray irradiation and correlation analysis with ATP, ADP, and adenosine as secondary soluble factors

[ 全著者名 ] Tomoya Fujie, Miyabi Kobayashi, Lihito Ikeuchi, Tsuyoshi Nakano, Kazuki Kitabatake, Yo Shinoda, Yasuyuki Fujiwara, Chika Yamamoto, Mitsutoshi Tsukimoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2024年 4月

[ 著作区分 ] レフェリー付学術論文（外国語）

Lead suppresses perlecan expression via EGFR-ERK1/2-COX-2-PGI2 pathway in cultured bovine vascular endothelial cells

[ 全著者名 ] Takato Hara, Reina Kumagai, Tohru Tanaka, Tsuyoshi Nakano, Tomoya Fujie, Yasuyuki Fujiwara, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2023年 12月

[ 著作区分 ] レフェリー付学術論文（外国語）

Pathogenesis of selective damage of granule cell layer in cerebellum of rats exposed to methylmercury

[ 全著者名 ] Ke Du, Takashi Hirooka, Yu Sasaki, Akira Yasutake, Takato Hara, Chika Yamamoto, Yasuyuki Fujiwara, Yo Shinoda, Tomoya Fujie, Shogo Katsuda, Komyo Eto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2023年 7月

[ 著作区分 ] レフェリー付学術論文（外国語）

Lead induces a metal transporter, ZIP8, via activation of the NF-κB signaling pathway and the induction is involved in the protection against lead cytotoxicity by intracellular lead accumulation independent mechanisms cultured vascular endothelial cells

[ 全著者名 ] Tomoya Fujie, Ayumi Muraoka, Keisuke Ito, Yusuke Ozaki, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2022年 11月

[ 著作区分 ] レフェリー付学術論文（外国語）

Induction of ZIP8, a ZIP transporter, via NF-κB signaling by the activation of IκBα and JNK signaling in cultured vascular endothelial cells exposed to cadmium

[ 全著者名 ] Tomoya Fujie, Keisuke Ito, Yusuke Ozaki, Suzuka Takahashi. Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] TOXICOLOGY AND APPLIED PHARMACOLOGY

[ 掲載年月 ] 2022年 1月

[ 著作区分 ] レフェリー付学術論文（外国語）

TGF-β1 potentiates the cytotoxicity of cadmium by induction of a metal transporter, ZIP8, mediated by the ALK5-Smad2/3 and ALK5-Smad3-p38 MAPK signal pathways in cultured vascular endothelial cells

[ 全著者名 ] Keisuke Ito, Tomoya Fujie, Masahiro Shimomura, Tsuyoshi Nakano, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

[ 掲載年月 ] 2022年 1月

[ 著作区分 ] レフェリー付学術論文（外国語）

Fibroblast growth factor-2 upregulates reactive sulfur species production via ERK1/2 signal-mediated cystathionine γ-lyase induction in cultured bovine aortic endothelial cells

[ 全著者名 ] Musubu Takahashi, Ayaka Kubota, Tomoya Fujie, Yasuhiro Shinkai, Yoshito Kumagai, Tsuyoshi Nakano, Takato Hara, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] BPB Reports

[ 掲載年月 ] 2021年 11月

[ 著作区分 ] レフェリー付学術論文（外国語）

Synthesis of reactive sulfur species in cultured vascular endothelial cells after exposure to TGF-β₁: induction of cystathionine γ-lyase and cystathionine β-synthase expression mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 pathways

[ 全著者名 ] Musubu Takahashi, Tomoya Fujie, Tsuyoshi Nakano, Takato Hara, Yasuhiro Shinkai, Ryoko Takasawa, Yasushi Hara, Yoshito Kumagai, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

[ 掲載年月 ] 2021年 10月

[ 著作区分 ] レフェリー付学術論文（外国語）

Sodium trisulfide, a sulfane sulfur donor, stimulates bovine aortic endothelial cell proliferation in culture

[ 全著者名 ] Musubu Takahashi, Ruri Iwai, Ryoko Takasawa, Tsuyoshi Nakano, Tomoya Fujie, Takato Hara, Yasushi Hara, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2021年 7月

[ 著作区分 ] レフェリー付学術論文（外国語）

Cadmium induces plasminogen activator inhibitor-1 via Smad2/3 signaling pathway in human endothelial EA.hy926 cells.

[ 全著者名 ] Takato Hara, Miki Sakuma, Tomoya Fujie, Toshiyuki Kaji, Chika Yamamoto

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2021年 5月

[ 著作区分 ] レフェリー付学術論文（外国語）

Induction of metallothionein isoforms in cultured bovine aortic endothelial cells exposed to cadmium

[ 全著者名 ] Tomoya Fujie, Yusuke Ozaki, Fukuta Takenaka, Misaki Nishio, Takato Hara, Yasuyuki Fujiwara, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2020年 12月

[ 著作区分 ] レフェリー付学術論文（外国語）

Zn(II)2,9-dimethyl-1,10-phenanthroline stimulates cultured bovine aortic endothelial cell proliferation

[ 全著者名 ] Takehiro Nakamura, Eiko Yoshida, Takato Hara, Tomoya Fujie, Chika Yamamoto, Yasuyuki Fujiwara, Fumihiko Ogata, Naohito Kawasaki, Ryo Takita, Masanobu Uchiyama, Toshiyuki Kaji

[ 掲載誌名 ] RSC Advances

[ 掲載年月 ] 2020年 11月

[ 著作区分 ] レフェリー付学術論文（外国語）

Transcriptional induction of cystathionine γ-lyase, a reactive sulfur-producing enzyme, by copper diethyldithiocarbamate in cultured vascular endothelial cells

[ 全著者名 ] Tomoya Fujie, Akane Takahashi, Musubu Takahashi, Takato Hara, Asuka Soyama, Kosho Makino, Hideyo Takahashi, Chika Yamamoto, Yoshito Kumagai, Hiroshi Naka, Toshiyuki Kaji

[ 掲載誌名 ] INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

[ 掲載年月 ] 2020年 8月

[ 著作区分 ] レフェリー付学術論文（外国語）

Possible mechanisms underlying transcriptional induction of metallothionein isoforms by tris(pentafluorophenyl)stibane, tris(pentafluorophenyl)arsane, and tris(pentafluorophenyl)phosphane in cultured bovine aortic endothelial cells

[ 全著者名 ] Tomoya Fujie, Fukuta Takenaka, Eiko Yoshida, Shuji Yasuike, Yasuyuki Fujiwara, Yasuhiro Shinkai, Yoshito Kumagai, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2019年 5月

[ 著作区分 ] レフェリー付学術論文（外国語）

Urinary trimethyl tin reflects blood trimethyl tin in workers recycling organotins

[ 全著者名 ] Gaku Ichihara, Mayu Iida, Eri Watanabe, Tomoya Fujie, Toshiyuki Kaji, Eunmi Lee, Yangho Kim

[ 掲載誌名 ] JOURNAL OF OCCUPATIONAL HEALTH

[ 掲載年月 ] 2019年 3月

[ 著作区分 ] レフェリー付学術論文（外国語）

Bis(1,4-dihydro-2-methyl-1-phenyl-4-thioxo-3-pyridiolato)zinc(II) exhibits strong cytotoxicity and a high intracellular accumulation in cultured vascular endothelial cells

[ 全著者名 ] Tomoya Fujie, Taro Yamamoto, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2019年 2月

[ 著作区分 ] レフェリー付学術論文（外国語）

Copper(II) bis(diethyldithiocarbamate) induces the expression of syndecan-4, a transmembrane heparan sulfate proteoglycan, via p38 MAPK activation in vascular endothelial cells

[ 全著者名 ] Takato Hara, HIroko Tatsuishi, Tomomi Banno, Tomoya Fujie, Chika Yamamoto, HIroshi Naka, Toshiyuki Kaji

[ 掲載誌名 ] INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

[ 掲載年月 ] 2018年 10月

[ 著作区分 ] レフェリー付学術論文（外国語）

Zinc complexes that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells

[ 全著者名 ] Akane Takahashi, Musubu Takahashi, Tomoya Fujie, Takato Hara, Eiko Yoshida, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] FUNDAMENTAL TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2018年 2月

[ 著作区分 ] レフェリー付学術論文（外国語）

Synergistic cytotoxicity caused by forming a complex of copper and 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells

[ 全著者名 ] Takehiro Nakamura, Eiko Yoshida, Tomoya Fujie, Fumihiko Ogata, Chika Yamamoto, Naohito Kawasaki, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2017年 12月

[ 著作区分 ] レフェリー付学術論文（外国語）

Copper diethyldithiocarbamate as an inhibitor of tissue plasminogen activator synthesis in cultured human coronary endothelial cells

[ 全著者名 ] Tomoya Fujie, Shiori Okino, Eiko Yoshida, Chika Yamamoto, Hiroshi Naka, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2017年 10月

[ 著作区分 ] レフェリー付学術論文（外国語）

Magnetic resonance imaging of leukoencephalopathy in amnestic workers exposed to organotin

[ 全著者名 ] Eunmi Lee, Ji Eun Park, Mayu Iida, Tomoya Fujie, Toshiyuki Kaji, Gaku Ichihara, Young Cheol Weon, Yangho Kim

[ 掲載誌名 ] NEUROTOXICOLOGY

[ 掲載年月 ] 2016年 12月

[ 著作区分 ] レフェリー付学術論文（外国語）

Toxicology of organic-inorganic hybrid molecules: Bio-organometallics and its toxicology

[ 全著者名 ] Tomoya Fujie, Takato Hara, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2016年 12月

[ 著作区分 ] レフェリー付学術論文（外国語）

Transcriptional induction of metallothionein by tris(pentafluorophenyl)stibane in cultured bovine aortic endothelial cells

[ 全著者名 ] Tomoya Fujie, Masaki Murakami, Eiko Yoshida, Shuji Yasuike, Tomoki Kimura, Yasuyuki Fujiwara, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

[ 掲載年月 ] 2016年 9月

[ 著作区分 ] レフェリー付学術論文（外国語）

Copper diethyldithiocarbamate as an activator of Nrf2 in cultured vascular endothelial cells

[ 全著者名 ] Tomoya Fujie, Masaki Murakami, Eiko Yoshida, Tadashi Tachinami, Yasuhiro Shinkai, Yasuyuki Fujiwara, Chika Yamamoto, Yoshito Kumagai, Hiroshi Naka, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

[ 掲載年月 ] 2016年 4月

[ 著作区分 ] レフェリー付学術論文（外国語）

Induction of metallothionein isoforms by copper diethyldithiocarbamate in cultured vascular endothelial cells

[ 全著者名 ] Tomoya Fujie, Yukino Segawa, Eiko Yoshida, Tomoki Kimura, Yasuyuki Fujiwara, Chika Yamamoto, Masahiko Satoh, Hiroshi Naka, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2016年 4月

[ 著作区分 ] レフェリー付学術論文（外国語）

Zinc diethyldithiocarbamate as an inducer of metallothionein in cultured vascular endothelial cells

[ 全著者名 ] Tomoya Fujie, Yukino Segawa, Akane Uehara, Takehiro Nakamura, Tomoki Kimura, Eiko Yoshida, Chika Yamamoto, Masanobu Uchiyama, Hiroshi Naka, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2016年 4月

[ 著作区分 ] レフェリー付学術論文（外国語）

The cytotoxicity of organobismuth compounds with certain molecular structures can be diminished by replacing the bismuth atom with an antimony atom in the molecules

[ 全著者名 ] Kumiko Kohri, Elko Yoshida, Shuji Yasuike, Tomoya Fujie, Chika Yamamoto, Toshiyuki Kaji

[ 掲載誌名 ] JOURNAL OF TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2015年 6月

[ 著作区分 ] レフェリー付学術論文（外国語）

Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells

[ 全著者名 ] Masaki Murakami,Tomoya Fujie, Mio Matsumura, Eiko Yoshida, Chika Yamamoto, Yasuyuki Fujiwara, Shuji Yasuike, Toshiyuki Kaji

[ 掲載誌名 ] FUNDAMENTAL TOXICOLOGICAL SCIENCES

[ 掲載年月 ] 2015年 4月