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Simple and Convenient Method for the Isolation, Culture, and Re-collection of Cancer Cells from Blood by Using Glass-Bead Filters
[ 全著者名 ] Babita Shashni, Hidehiko Matsuura, Riku Saito, Takuma Hirata, Shinya Ariyasu, Kenta Nomura, Hiroshi Takemura, Kazunori Akimoto, Naoyuki Aikawa, Atsuo Yasumori and Shin Aoki
[ 掲載誌名 ] ACS Biomaterials Science & Engineering
[ 掲載年月 ] 2019年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
Atypical Protein Kinase C λ/ι Expression is Associated with Malignancy of Oral Squamous Cell Carcinoma
[ 全著者名 ] JUNICHI BABA, MITOMU KIOI, KAZUNORI AKIMOTO, YOJI NAGASHIMA, MASATAKA TAGURI, YOSHIAKI INAYAMA, ICHIRO AOKI, SHIGEO OHNO, KENJI MITSUDO and IWAI TOHNAI
[ 掲載誌名 ] ANTICANCER RESEARCH
[ 掲載年月 ] 2018年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells
[ 全著者名 ] Shoma Tamori, Yuka Nozaki, Hitomi Motomura, Hiromi Nakane, Reika Katayama, Chotaro Onaga, Eriko Kikuchi, Nami Shimada, Yuhei Suzuki, Mei Noike, Yasushi Hara, Keiko Sato, Tsugumichi Sato, Kouji Yamamoto, Takehisa Hanawa, Misa Imai, Ryo Abe, Atsushi Yoshimori, Ryoko Takasawa, Sei-Ichi Tanuma and Kazunori Akimoto
[ 掲載誌名 ] Oncotarget
[ 掲載年月 ] 2018年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Aberrant nuclear localization of aPKCλ/ι is associated with poorer prognosis in uterine cervical cancer
[ 全著者名 ] Aya Tokinaga-Uchiyama, Taichi Mizushima, Kazunori Akimoto, Yoji Nagashima, Kazunori Sasaki, Masa-aki Nakaya, Kenichi Ohashi, Kazumi Kubota, Yasuyo Maruyama, Hisamori Kato, Fumiki Hirahara, Etsuko Miyagi, Shigeo Ohno, Mikiko Asai-Sato
[ 掲載誌名 ] INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
[ 掲載年月 ] 2018年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Size-based Differentiation of Cancer and Normal Cells by a Particle Size Analyzer Assisted by a Cell-recognition PC Software
[ 全著者名 ] Babita Shashni, Shinya Ariyasu, Reisa Takeda, Toshihiro Suzuki, Shota Shiina, Kazunori Akimoto, Takuto Maeda, Naoyuki Aikawa, Ryo Abe, Tomorhiro Osaki, Norihiko Itoh, and Shin Aoki
[ 掲載誌名 ] Biological and Pharmaceutical Bulletin
[ 掲載年月 ] 2018年 4月
[ 著作区分 ] レフェリー付学術論文(外国語)
Correlation between c-Met and ALDH1 contributes to the survival and tumor-sphere formation of ALDH1 positive breast cancer stem cells and predicts poor clinical outcome in breast cancer
[ 全著者名 ] Yuka Nozaki, Shoma Tamori, Masahiro Inada, Reika Katayama, Hiromi Nakane, Osamu Minamishima, Yuka Onodera, Makoto Abe, Shota Shiina, Kei Tamura, Daichi Kodama, Keiko Sato, Yasushi Hara, Ryo Abe, Ryoko Takasawa, Atsushi Yoshimori, Nariyoshi Shinomiya, Sei-ichi Tanuma and Kazunori Akimoto*
[ 掲載誌名 ] GENES & CANCER
[ 掲載年月 ] 2017年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Expression Levels of KMT2C and SLC20A1 identified by information-theoretical analysis are powerful prognostic biomarkers in ER-positive breast cancer
[ 全著者名 ] Keiko Sato and Kazunori Akimoto
[ 掲載誌名 ] Clinical Breast Cancer
[ 掲載年月 ] 2017年 6月
[ 著作区分 ] レフェリー付学術論文(外国語)
Aberrant expression of the cell-polarity regulator aPKC λ/ι is associated with disease progression in cervical intraepithelial neoplasia (CIN): a possible marker for predicting CIN prognosis
[ 全著者名 ] Taichi Mizushima, Mikiko Asai-Sato, Kazunori Akimoto,Yoji Nagashima, Masataka Taguri, Kazunori Sasaki, Masa-aki Nakaya, Ryoko Asano, Aya Tokinaga, Tohru Kiyono, Fumiki Hirahara, Shigeo Ohno, Etsuko Miyagi
[ 掲載誌名 ] INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
[ 掲載年月 ] 2016年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates.
[ 全著者名 ] Metz PJ, Lopez J, Kim SH, Akimoto K, Ohno S, Chang JT.
[ 掲載誌名 ] Scientific Reports
[ 掲載年月 ] 2016年 1月
[ 著作区分 ] レフェリー付学術論文(外国語)
Atypical Protein Kinase C Isoform, aPKCλ, is Essential for Maintaining Hair Follicle Stem Cell Quiescence
[ 全著者名 ] Shin-Ichi Osada, Minematsu Naoko, Fumino Oda, Kazunori Akimoto, Seiji Kawana and Shigeo Ohno
[ 掲載誌名 ] JOURNAL OF INVESTIGATIVE DERMATOLOGY
[ 掲載年月 ] 2015年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Regulation of epithelial cell polarity by PAR-3 depends on Girdin transcription and Girdin-Gαi3 signaling
[ 全著者名 ] Kazunori Sasaki, Taku Kakuwa, Kazunori Akimoto, Hisashi Koga, Shigeo Ohno
[ 掲載誌名 ] JOURNAL OF CELL SCIENCE
[ 掲載年月 ] 2015年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Regulation of Asymmetric Division and CD8+ T Lymphocyte Fate Specification by PKCζ and PKCλ/ι
[ 全著者名 ] Patrick J. Metz, Janilyn Arsenio, Boyko Kakaradov, Stephanie H. Kim,Kelly A. Remedios, Katherine Oakley, Kazunori Akimoto, Shigeo Ohno, Gene W. Yeo, John T. Chang
[ 掲載誌名 ] JOURNAL OF IMMUNOLOGY
[ 掲載年月 ] 2015年 3月
[ 著作区分 ] レフェリー付学術論文(外国語)
Proteomic analysis of proteins related to prognosis of lung adenocarcinoma
[ 全著者名 ] Okayama, Akiko; Miyagi, Yohei; Oshita, Fumihiro; Nishi, Mayuko; Nakamura, Yoshiyasu; Nagashima, Yoji; Akimoto, Kazunori; Ryo, Akihide; Hirano, Hisashi
[ 掲載誌名 ] JOURNAL OF PROTEOME RESEARCH
[ 掲載年月 ] 2014年 11月
[ 著作区分 ] レフェリー付学術論文(外国語)
Colorectal laterally spreading tumors show characteristic expression of cell polarity factors, including atypical protein kinase C λ/ι, E-cadherin, β-catenin and basement membrane component.
[ 全著者名 ] Ichikawa Y, Nagashima Y, Morioka K, Akimoto K, Kojima Y, Ishikawa T, Goto A, Kobayashi N, Watanabe K, Ota M, Fujii S, Kawamata M, Takagawa R, Kunizaki C, Takahashi H, Nakajima A, Maeda S, Shimada H, Inayama Y, Ohno S, Endo I.
[ 掲載誌名 ] Oncology Letters
[ 掲載年月 ] 2014年 9月
[ 著作区分 ] レフェリー付学術論文(外国語)
Loss of aPKCl in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brain
[ 全著者名 ] Yamanaka T., Tosaki A., Kurosawa M., Akimoto K., Hirose T., Ohno S.,Hattori N., and Nukina N.
[ 掲載誌名 ] PLoS One
[ 掲載年月 ] 2013年 12月
[ 著作区分 ] レフェリー付学術論文(外国語)
aPKCλ/ι is a beneficial prognostic marker for pancreatic neoplasms
[ 全著者名 ] Shingo Kato, Kazunori Akimoto, Yoji Nagashima, Hitoshi Ishiguro, Kensuke Kubota, Noritoshi Kobayashi, Kunihiro Hosono, Seitaro Watanabe, Yusuke Sekino, Takamitsu Sato, Kazunori Sasaki, Noboru Nakaigawa, Yoshinobu Kubota, Yoshiaki Inayama, Itaru Endo, Shigeo Ohno, Shin Maeda, Atsushi Nakajima.
[ 掲載誌名 ] PANCREATOLOGY
[ 掲載年月 ] 2013年 8月
[ 著作区分 ] レフェリー付学術論文(外国語)
Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos
[ 全著者名 ] Yoshikazu Hirate, Shino Hirahara, Ken-ichi Inoue, Atsushi Suzuki, Vernadeth B. Alarcon, Kazunori Akimoto, Takaaki Hirai, Takeshi Hara, Makoto Adachi, Kazuhiro Chida, Shigeo Ohno, Yusuke Marikawa, Kazuki Nakao, Akihiko Shimono, Hiroshi Sasaki
[ 掲載誌名 ] CURRENT BIOLOGY
[ 掲載年月 ] 2013年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
Cleavage of the interchain disulfide bonds in rituximab increases its affinity for Fcgamma RIIIA
[ 全著者名 ] Mami Suzuki, Ayaka Yamanoi, Yusuke Machino, Eiji Kobayashi, Kaori Fukuchi, Mitsutoshi Tsukimoto, Shuji Kojima, Junya Kohroki, Kazunori Akimoto, and Yasuhiko Masuho.
[ 掲載誌名 ] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
[ 掲載年月 ] 2013年 7月
[ 著作区分 ] レフェリー付学術論文(外国語)
High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis.
[ 全著者名 ] Yoshihama Y, Izumisawa Y, Akimoto K(corresponding author), Satoh Y, Mizushima T, Satoh K, Chida K, Takagawa R, Akiyama H, Ichikawa Y, Kunisaki C, Inayama Y, Endo I, Nagashima Y, Ohno S.
[ 掲載誌名 ] CANCER SCIENCE
[ 掲載年月 ] 2013年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
KIBRA-aPKC Connection: High expression of KIBRA in High Invasion and Poor Prognosis. Overexpression of the aPKC-binding region of KIBRA affects tight junction formation in epithelial cells
[ 全著者名 ] Yoshihama Y, Izumisawa Y, Akimoto K(corresponding author), Satoh Y, Mizushima T, Satoh K, Chida K, Takagawa R, Akiyama H, Ichikawa Y, Kunisaki C, Inayama Y, Endo I, Nagashima Y, Ohno S. Cover
[ 掲載誌名 ] CANCER SCIENCE
[ 掲載年月 ] 2013年 2月
[ 著作区分 ] レフェリー付学術論文(外国語)
The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence
[ 全著者名 ] Hitoshi Ishiguro, Kazunori Akimoto, Yoji Nagashima, Eriko Kagawa, Takeshi Sasaki, Sano JY, Ryo Takagawa, Fujinami K, Kazunori Sasaki, Ichiro Aoki, Shigeo Ohno, Yoshinobu Kubota , Hiroji Umemura.
[ 掲載誌名 ] CANCER SCIENCE
[ 掲載年月 ] 2011年
[ 著作区分 ] レフェリー付学術論文(外国語)
High Expression of Atypical Protein Kinase C λ/ι in Gastric Cancer as a Prognostic Factor for Recurrence
[ 全著者名 ] Ryo Takagawa, Kazunori Akimoto, Yasushi Ichikawa, Hirotoshi Akiyama, Itaru Endo, Yasuyuki Kojima, Hitoshi Ishiguro, Yoshiaki Inayama, Ichiro Aoki, Chikara Kunisaki, Yoji Nagashima, and Shigeo Ohno
[ 掲載誌名 ] ANNALS OF SURGICAL ONCOLOGY
[ 掲載年月 ] 2010年
[ 著作区分 ] レフェリー付学術論文(外国語)
An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms
[ 全著者名 ] Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S.
[ 掲載誌名 ] PLOS ONE
[ 掲載年月 ] 2009年
[ 著作区分 ] レフェリー付学術論文(外国語)
A cell polarity protein aPKC lambda is required for eye lens formation and growth
[ 全著者名 ] Yuki Sugiyama, Kazunori Akimoto, Michael L Robinson, Shigeo Ohno and Roy A Quinlan.
[ 掲載誌名 ] DEVELOPMENTAL BIOLOGY
[ 掲載年月 ] 2009年
[ 著作区分 ] レフェリー付学術論文(外国語)
aPKCλ/ι promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6
[ 全著者名 ] Hitoshi Ishiguro, Kazunori Akimoto, Yoji Nagashima, Yasuyuki Kojima, Takeshi Sasaki, Yukari Ishiguro-Imagawa, Noboru Nakaigawa, Shigeo Ohno, Yoshinobu Kubota, and Hiroji Uemura.
[ 掲載誌名 ] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
[ 掲載年月 ] 2009年
[ 著作区分 ] レフェリー付学術論文(外国語)
The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors
[ 全著者名 ] Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ishikawa T, Sasaki T, Kubota Y, Inayama Y, Aoki I, Ohno S, Shimada H.
[ 掲載誌名 ] HUMAN PATHOLOGY
[ 掲載年月 ] 2008年
[ 著作区分 ] レフェリー付学術論文(外国語)
PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains
[ 全著者名 ] Hirose T, Karasawa M, Sugitani Y, Fujisawa M, Akimoto K, Ohno S, Noda T.
[ 掲載誌名 ] DEVELOPMENT
[ 掲載年月 ] 2006年
[ 著作区分 ] レフェリー付学術論文(外国語)
Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex
[ 全著者名 ] Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S.
[ 掲載誌名 ] DEVELOPMENT
[ 掲載年月 ] 2006年
[ 著作区分 ] レフェリー付学術論文(外国語)
PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells
[ 全著者名 ] Hashimoto N, Kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H, Matsumoto M, Ogawa W, Maeda S, Fujihara H, Ueta Y, Uchiyama Y, Akimoto K, Ohno S, Noda T, Kasuga M.
[ 掲載誌名 ] JOURNAL OF CLINICAL INVESTIGATION
[ 掲載年月 ] 2005年
[ 著作区分 ] レフェリー付学術論文(外国語)
Function of atypical protein kinase C lambda in differentiating photoreceptors is required for proper lamination of mouse retina
[ 全著者名 ] Koike C, Nishida A, Akimoto K, Nakaya MA, Noda T, Ohno S, Furukawa T.
[ 掲載誌名 ] JOURNAL OF NEUROSCIENCE
[ 掲載年月 ] 2005年
[ 著作区分 ] レフェリー付学術論文(外国語)
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